The global antimicrobial resistance crisis poses a significant threat to humankind in the
coming decades. Challenges associated with the development of novel antibiotics …

Tuberculosis (TB) has been troubling humans for hundreds of years, is a highly infectious
disease caused by Mycobacterium tuberculosis (Mtb) infection, Mtb can infect almost all …

Tuberculosis caused by Mycobacterium tuberculosis remains a serious global public health
threat. M. tuberculosis PE and PPE proteins are closely involved in pathogen-host …

Objectives The host immune response towards Mycobacterium tuberculosis (M. tb) is known
to vary with the virulence of mycobacterial species. While the majority of M. tb-exposed …

The JAK/STAT and NFκB signaling pathways are two major inflammatory signaling
pathways that are usually activated simultaneously in the body's inflammatory response to …

Several factors are associated with the development of different clinical forms of tuberculosis
(TB). The present study evaluated epidemiological variables and cytokine levels in samples …

Abstract JAK/STAT and NFκB signalling pathways play essential roles in regulating
inflammatory responses, which are important pathogenic factors of various serious immune …

Peptidoglycan (PG), a heteropolysaccharide component of the mycobacterial cell wall can
be shed during tuberculosis infection with immunomodulatory consequences. As such …

The nature of the culture dish surface and the technique used to detach adherent cells could
very likely influence the cell viability and cell membrane protein integrity of harvested …

Background. Tuberculosis is a bacterial infection that is caused by Mycobacterium
tuberculosis. Tuberculosis has arguably been the largest killer of humans historically, and it …