Abstract Purpose of Review Bipolar disorder has the highest rate of suicide of all psychiatric
conditions and is approximately 20–30 times that of the general population. The purpose of …

Bipolar disorders (BDs) are prevalent mental health illnesses that affect about 1–5% of the
total population, have a chronic course and are associated with a markedly elevated …

We summarize evidence supporting contemporary pharmacological treatment of phases of
BD, including: mania, depression, and long-term recurrences, emphasizing findings from …

Importance Electroconvulsive therapy (ECT) is indicated for severe depression, including
depression with psychosis, catatonia, and/or an elevated suicide risk. However, the …

Objective Single-dose intravenous (IV) injection of ketamine has shown rapid but transient
antidepressant effects. The strategy of repeated-dose ketamine infusions to maintain …

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Background Excess mortality is a critical hallmark of bipolar disorder (BD) due to co‐
occurring general medical disorders and especially from suicide. It is timely to review of the …

Objective In this systematic review and meta‐analysis, the response, remission, and speed
of response in adults with major depressive disorder (MDD) and bipolar disorder in …

Importance The risk of substance use disorder (SUD) in patients with autism spectrum
disorder (ASD) remains unclear. Objective To investigate the risk of SUD in patients with …

Background Suicide is a public health crisis. We conducted a systematic review and meta‐
analysis of the effects of psychopharmacologic and somatic therapies on suicide risk …