The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation

RG Pestell, C Albanese, AT Reutens… - Endocrine …, 1999 - academic.oup.com
A. Single-transmembrane segment receptors B. Seven-transmembrane receptors C. Steroid
hormones D. Intracellular second messengers IV. Cyclins and CKIs in Endocrine Tumors A …

Cyclic AMP signaling and gene regulation

PB Daniel, WH Walker, JF Habener - Annual review of nutrition, 1998 - annualreviews.org
▪ Abstract Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger
produced in cells in response to hormones and nutrients. The production of cAMP is …

CREB activation induces adipogenesis in 3T3-L1 cells

JEB Reusch, LA Colton, DJ Klemm - Molecular and cellular biology, 2000 - Taylor & Francis
Obesity is the result of numerous, interacting behavioral, physiological, and biochemical
factors. One increasingly important factor is the generation of additional fat cells, or …

Transcriptional regulation by cyclic AMP-responsive factors

D De Cesare, P Sassone-Corsi - 2000 - Elsevier
In eukaryotes, transcriptional regulation on stimulation of the adenylate cyclase signaling
pathway is mediated by a family of cyclic AMP-responsive nuclear factors, including CREB …

A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM

GM Fimia, D De Cesare… - Molecular and Cellular …, 2000 - Taylor & Francis
Transcription factors of the CREB family control the expression of a large number of genes in
response to various signaling pathways. Regulation mediated by members of the CREB …

Coupling cAMP signaling to transcription in the liver: pivotal role of CREB and CREM

G Servillo, MA Della Fazia, P Sassone-Corsi - Experimental cell research, 2002 - Elsevier
Transcriptional factors binding to cAMP-responsive elements (CREs) in the promoters of
various genes belong to the basic domain-leucine zipper superfamily and are composed of …

Inducible cAMP early repressor (ICER) is a negative-feedback regulator of cardiac hypertrophy and an important mediator of cardiac myocyte apoptosis in response to …

H Tomita, M Nazmy, K Kajimoto, G Yehia… - Circulation …, 2003 - Am Heart Assoc
Although stimulation of the β-adrenergic receptor increases levels of cAMP and activation of
the cAMP response element (CRE) in cardiac myocytes, the role of the signaling mechanism …

NADPH oxidase-derived reactive oxygen species mediate decidualization of human endometrial stromal cells in response to cyclic AMP signaling

M Al-Sabbagh, L Fusi, J Higham, Y Lee, K Lei… - …, 2011 - academic.oup.com
Differentiation of human endometrial stromal cells into specialized decidual cells is critical
for embryo implantation and survival of the conceptus. Initiation of this differentiation process …

Molecular defects in the pathogenesis of pituitary tumours

A Levy, S Lightman - Frontiers in Neuroendocrinology, 2003 - Elsevier
The majority of pituitary adenomas are trophically stable and change relatively little in size
over many years. A comparatively small proportion behave more aggressively and come to …

Inducible cAMP early repressor (ICER) in the nervous system–a transcriptional regulator of neuronal plasticity and programmed cell death

B Mioduszewska, J Jaworski… - Journal of …, 2003 - Wiley Online Library
The acronym ICER (inducible cAMP early repressor) refers to a group of four proteins
produced from the CREM/ICER gene due to use of an internal promoter (P2) placed in an …