[HTML][HTML] Modern tools for rapid diagnostics of antimicrobial resistance

A Vasala, VP Hytönen, OH Laitinen - Frontiers in cellular and infection …, 2020 - frontiersin.org
Fast, robust, and affordable antimicrobial susceptibility testing (AST) is required, as roughly
50% of antibiotic treatments are started with wrong antibiotics and without a proper …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

[HTML][HTML] Bloodstream infections in critically ill patients: an expert statement

JF Timsit, E Ruppé, F Barbier, A Tabah… - Intensive care medicine, 2020 - Springer
Bloodstream infection (BSI) is defined by positive blood cultures in a patient with systemic
signs of infection and may be either secondary to a documented source or primary—that is …

Innovative and rapid antimicrobial susceptibility testing systems

A van Belkum, CAD Burnham, JWA Rossen… - Nature Reviews …, 2020 - nature.com
Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid
detection and quantification of resistance, combined with antimicrobial stewardship, are key …

[HTML][HTML] Fighting antibiotic resistance in hospital-acquired infections: current state and emerging technologies in disease prevention, diagnostics and therapy

E Avershina, V Shapovalova, G Shipulin - Frontiers in microbiology, 2021 - frontiersin.org
Rising antibiotic resistance is a global threat that is projected to cause more deaths than all
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …

[HTML][HTML] Diagnosis of bloodstream infections from positive blood cultures and directly from blood samples: recent developments in molecular approaches

N Peker, N Couto, B Sinha, JW Rossen - Clinical Microbiology and …, 2018 - Elsevier
Background Bloodstream infections are a major cause of death with increasing incidence
and severity. Blood cultures are still the reference standard for microbiological diagnosis, but …

[HTML][HTML] Bloodstream infections–Standard and progress in pathogen diagnostics

B Lamy, M Sundqvist, EA Idelevich - Clinical Microbiology and Infection, 2020 - Elsevier
Background Bloodstream infection (BSI) is a major public health burden worldwide, with
high mortality. Patient outcome is critically influenced by delayed therapy, and fast and …

Biofilm antimicrobial susceptibility testing: where are we and where could we be going?

T Coenye - Clinical microbiology reviews, 2023 - Am Soc Microbiol
Our knowledge about the fundamental aspects of biofilm biology, including the mechanisms
behind the reduced antimicrobial susceptibility of biofilms, has increased drastically over the …

Antibiotic use in the intensive care unit: optimization and de-escalation

M Campion, G Scully - Journal of intensive care medicine, 2018 - journals.sagepub.com
Appropriate antimicrobial therapy is essential to ensuring positive patient outcomes.
Inappropriate or suboptimal utilization of antibiotics can lead to increased length of stay …

Accurate identification of clinically important Acinetobacter spp.: an update

S Vijayakumar, I Biswas, B Veeraraghavan - Future science OA, 2019 - Taylor & Francis
Acinetobacter species have emerged as one of the most clinically important pathogens. The
phenotypic techniques which are currently available are insufficient in accurately identifying …