Rats and mice are attracted by novel objects. They readily approach novel objects and
explore them with their vibrissae, nose and forepaws. It is assumed that such a single …

Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

The ascending serotonin (5-HT) neurons innervate the cerebral cortex, hippocampus,
septum and amygdala, all representing brain regions associated with various domains of …

Serotonin [5-hydroxytryptamine (5-HT)] is a multifunctional neurotransmitter innervating
cortical and limbic areas involved in cognition and emotional regulation. Dysregulation of …

Abstract Serotonin, or 5-hydroxytryptamine (5-HT), is found to be involved in many
physiological or pathophysiological processes including cognitive function. Seven distinct …

The serotonergic system is involved in diverse cognitive functions including memory. Of
particular importance to daily life are declarative memories that contain information about …

Abstract Nanoplastics (NPs) and arsenic (As) are toxic pollutants prevalent on the earth and
have gained considerable attention in recent decades. Although numerous studies reported …

Compounds enhancing N-methyl-d-aspartate (NMDA) glutamate receptor function have
been reported to improve cognitive deficits. Since cognitive deficits are considered to be the …

Objective To review the evidence that agents which preferentially affect serotonin (5-HT)
attenuate the ability of N-methyl-D-aspartate (NMDA) receptor non-competitive antagonists …

The concept that the efficacy of all antipsychotic drugs (APDs) can be explained by their
action on dopamine (DA) D2 receptors is most challenged by drugs such as clozapine which …