Reactive oxygen species (ROS), a class of highly bioactive molecules, have been widely
studied in various types of cancers. ROS are considered to be normal byproducts of …

Objectives Green tea (Camellia sinensis) is a kind of unfermented tea that retains the natural
substance in fresh leaves to a great extent. It is regarded as the second most popular drink …

In pathophysiology, reactive oxygen species control diverse cellular phenotypes by
oxidizing biomolecules. Among these, the guanine base in nucleic acids is the most …

Reactive oxygen species are a constant threat to DNA as they modify bases with the risk of
disrupting genome function, inducing genome instability and mutation. Such risks are due to …

The relationships between inflammation and cancer are varied and complex. An important
connection linking inflammation to cancer development is DNA damage. During …

An unanswered question in human health is whether antioxidation prevents or promotes
cancer. Antioxidation has historically been viewed as chemopreventive, but emerging …

The rate of skin aging, or that of tissue in general, is determined by a variable predominance
of tissue degeneration over tissue regeneration. This review discusses the role of oxidative …

Objectives For over a century, a heated debate existed over the possibility of malignant
transformation of oral lichen planus (OLP). We performed this meta-analysis to evaluate the …

DNA damage created by endogenous or exogenous genotoxic agents can exist in multiple
forms, and if allowed to persist, can promote genome instability and directly lead to various …

Reactive oxygen species (ROS) are mutagenic and may thereby promote cancer. Normally,
ROS levels are tightly controlled by an inducible antioxidant program that responds to …