Antibiotics, resistome and resistance mechanisms: A bacterial perspective

I Sultan, S Rahman, AT Jan, MT Siddiqui… - Frontiers in …, 2018 - frontiersin.org
History of mankind is regarded as struggle against infectious diseases. Rather than
observing the withering away of bacterial diseases, antibiotic resistance has emerged as a …

Resistance integrons: class 1, 2 and 3 integrons

Y Deng, X Bao, L Ji, L Chen, J Liu, J Miao… - Annals of clinical …, 2015 - Springer
As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary
treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for …

The prevalence of integrons as the carrier of antibiotic resistance genes in natural and man-made environments

L Ma, AD Li, XL Yin, T Zhang - Environmental science & …, 2017 - ACS Publications
Class 1 integrase int I1 has been considered as a good proxy for anthropogenic pollution
because of being linked to genes conferring resistance to antibiotics. The gene cassettes of …

Metagenomic assembly reveals hosts of antibiotic resistance genes and the shared resistome in pig, chicken, and human feces

L Ma, Y Xia, B Li, Y Yang, LG Li… - … science & technology, 2016 - ACS Publications
The risk associated with antibiotic resistance disseminating from animal and human feces is
an urgent public issue. In the present study, we sought to establish a pipeline for annotating …

The human microbiome as a reservoir of antimicrobial resistance

J Penders, EE Stobberingh, PHM Savelkoul… - Frontiers in …, 2013 - frontiersin.org
The gut microbiota is amongst the most densely populated microbial ecosystem on earth.
While the microbiome exerts numerous health beneficial functions, the high density of micro …

Integrons in the development of antimicrobial resistance: critical review and perspectives

BA Bhat, RA Mir, H Qadri, R Dhiman… - Frontiers in …, 2023 - frontiersin.org
Antibiotic resistance development and pathogen cross-dissemination are both considered
essential risks to human health on a worldwide scale. Antimicrobial resistance genes …

ESBL-Producing Escherichia coli from Cows Suffering Mastitis in China Contain Clinical Class 1 Integrons with CTX-M Linked to ISCR1

T Ali, S ur Rahman, L Zhang, M Shahid… - Frontiers in …, 2016 - frontiersin.org
The prevalence of pathogenic multi-drug resistant (MDR) extended-spectrum β-lactamase
(ESBL)-producing Escherichia coli is rapidly increasing, becoming a global concern. In a …

Integrons in Enterobacteriaceae: diversity, distribution and epidemiology

M Kaushik, S Kumar, RK Kapoor, JS Virdi… - International journal of …, 2018 - Elsevier
Integrons are versatile gene acquisition systems that allow efficient capturing of exogenous
genes and ensure their expression. Various classes of integrons possessing a wide variety …

Host bacterial community of MGEs determines the risk of horizontal gene transfer during composting of different animal manures

L Zhu, Y Zhao, K Yang, J Chen, H Zhou, X Chen… - Environmental …, 2019 - Elsevier
Mobile genetic elements (MGEs) play critical roles in transferring antibiotic resistance genes
(ARGs) among different microorganisms in the environment. This study aimed to explore the …

Commensal Escherichia coli of healthy humans: a reservoir for antibiotic-resistance determinants

JK Bailey, JL Pinyon, S Anantham… - Journal of medical …, 2010 - microbiologyresearch.org
This study examined in detail the population structure of Escherichia coli from healthy adults
with respect to the prevalence of antibiotic resistance and specific resistance determinants …