Background Bipolar disorder (BD) is associated with premature death and ischemic heart
disease is the main cause of excess mortality. Heart rate variability (HRV) predicts mortality …

Bipolar disorder (BD) has been previously associated with clinical signs of premature aging,
including accelerated epigenetic aging in blood and brain, and a steeper age-related …

Background Overall functioning is already impaired in patients newly diagnosed with bipolar
disorder (BD) and, to a lesser degree, also in their unaffected first-degree relatives (UR) …

Introduction The manifestation of bipolar disorder (BD) is hypothesized to be determined by
clinical characteristics such as familial loading, childhood abuse, age at onset, illness …

Background To identify prospectively ascertained individual and family factors that are
associated with improvement in Bipolar Disorder (BD) among youths who initially presented …

With the advancements in gene sequencing technologies, including genome-wide
association studies, polygenetic risk scores, and high-throughput sequencing, there has …

Bipolar disorder (BD) is a complex mental health disorder with a heterogenous clinical
course, diagnostic delays, high relapse rates, and sub-optimal treatment outcomes. Age at …

Recent mental health research has highlighted the critical role of inflammation in conditions
like depression and bipolar disorder, examining correlations with markers such as calcium …

Social cognition might be impaired in first degree relatives (FDR) of BD but existing research
shows controversial results about social cognitive impairments in this population. The aim of …