Since the publication of the first genome-wide association study for cancer in 2007,
thousands of common alleles that are associated with the risk of cancer have been …

Ovarian cancer (OC) is one of the leading causes of cancer-related deaths in women. Most
patients are diagnosed with advanced epithelial OC in their late 60s, and early-onset adult …

Background Epithelial tubo-ovarian cancer (EOC) has high mortality partly due to late
diagnosis. Prevention is available but may be associated with adverse effects. A …

Background BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier
Estimation Algorithm) for breast cancer and the epithelial tubo-ovarian cancer (EOC) models …

Background Ovarian cancer is among the leading causes of gynecologic cancer-related
death. Past ovarian cancer screening trials using combination of cancer antigen 125 testing …

The subset of ovarian cancer (OC) diagnosed≤ 30yo represents a distinct subgroup
exhibiting disparities from late-onset OC in many aspects, including indefinite germline …

Importance Frequent aspirin use is associated with reduced ovarian cancer risk, but it is
unknown whether genetic factors modify this association. Understanding effect modifiers is …

We conducted a genome-wide association study (GWAS) in a multiethnic cohort of 920 at-
risk infants for retinopathy of prematurity (ROP), a major cause of childhood blindness …

Recommendations are graded as per the Royal College of Obstetricians and
Gynaecologists document, Clinical Governance Advice No. 1: Guidance for the …

Background Early-onset cancer (diagnosed under age 50) generally manifests as an
aggressive disease phenotype. The association between healthy lifestyle and early-onset …