Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Multifunctional nanotheranostics for near infrared optical imaging-guided treatment of brain tumors

L Zhang, Y Liu, H Huang, H Xie, B Zhang, W Xia… - Advanced drug delivery …, 2022 - Elsevier
Malignant brain tumors, a heterogeneous group of primary and metastatic neoplasms in the
central nervous system (CNS), are notorious for their highly invasive and devastating …

Nanoparticles for targeted brain drug delivery: what do we know?

RGR Pinheiro, AJ Coutinho, M Pinheiro… - International Journal of …, 2021 - mdpi.com
The blood–brain barrier (BBB) is a barrier that separates the blood from the brain tissue and
possesses unique characteristics that make the delivery of drugs to the brain a great …

Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics

W Tang, W Fan, J Lau, L Deng, Z Shen… - Chemical Society …, 2019 - pubs.rsc.org
Brain cancer, especially the most common type of glioblastoma, is highly invasive and
known as one of the most devastating and deadly neoplasms. Despite surgical and medical …

Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Crossing the blood–brain barrier: recent advances in drug delivery to the brain

MM Patel, BM Patel - CNS drugs, 2017 - Springer
CNS disorders are on the rise despite advancements in our understanding of their
pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the …

[HTML][HTML] Progress and perspectives on targeting nanoparticles for brain drug delivery

H Gao - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Due to the ability of the blood–brain barrier (BBB) to prevent the entry of drugs into the brain,
it is a challenge to treat central nervous system disorders pharmacologically. The …

Rethinking CRITID procedure of brain targeting drug delivery: circulation, blood brain barrier recognition, intracellular transport, diseased cell targeting, internalization …

S Ruan, Y Zhou, X Jiang, H Gao - Advanced Science, 2021 - Wiley Online Library
The past decades have witnessed great progress in nanoparticle (NP)‐based brain‐
targeting drug delivery systems, while their therapeutic potentials are yet to be fully exploited …

Nanomaterials for photothermal and photodynamic cancer therapy

B Nasseri, E Alizadeh, F Bani, S Davaran… - Applied Physics …, 2022 - pubs.aip.org
In recent years, the role of optically sensitive nanomaterials has become powerful moieties
in therapeutic techniques and has become particularly emphasized. Currently, by the …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …