Dysfunction of VAMP-associated protein (VAP) is associated with neurodegeneration, both
Amyotrophic Lateral Sclerosis and Parkinson's disease. Here we summarize what is known …

The Endoplasmic Reticulum (ER) is an endomembrane system that plays a multiplicity of
roles in cell physiology and populates even the most distal cell compartments, including …

Summary VAP (VAPA and VAPB) is an evolutionarily conserved endoplasmic reticulum (ER)-
anchored protein that helps generate tethers between the ER and other membranes through …

To coordinate cellular physiology, eukaryotic cells rely on the rapid exchange of molecules
at specialized organelle–organelle contact sites,. Endoplasmic reticulum–mitochondrial …

Identification of targeted therapies for TNBC is an urgent medical need. Using a drug
combination screen reliant on synthetic lethal interactions, we identified clinically relevant …

A proline to serine substitution at position 56 in the gene encoding vesicle-associated
membrane protein-associated protein B (VAPB) causes some dominantly inherited familial …

Peroxisomes (POs) and the endoplasmic reticulum (ER) cooperate in cellular lipid
metabolism and form tight structural associations, which were first observed in ultrastructural …

In eukaryotic cells, mitochondria are closely tethered to the endoplasmic reticulum (ER) at
sites called mitochondria‐associated ER membranes (MAMs). Ca2+ ion and phospholipid …

The endoplasmic reticulum (ER) plays important roles in protein synthesis and folding, and
calcium storage. The volume of the ER and expression of its resident proteins are increased …

Kv2. 1 exhibits two distinct forms of localization patterns on the neuronal plasma membrane:
One population is freely diffusive and regulates electrical activity via voltage-dependent K+ …