Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Abstract Allopregnanolone, a 3α, 5α‐progesterone metabolite, acts as a potent allosteric
modulator of the γ‐aminobutyric acid type A receptor. In the present review, the synthesis of …

Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …

Real concerns exist over the impacts of biodiversity loss. This loss is increasing following
population pollution, which is producing strong impacts. There is a strong determination to …

High glucose (HG)-induced nucleotide-binding and oligomerization (NACHT) domain,
leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3 (NLRP3) …

The nervous system, in addition to be a target for steroid hormones, is the source of a variety
of neuroactive steroids, which are synthesized and metabolized by neurons and glial cells …

Abstract Allopregnanolone (3α, 5α-tetrahydroprogesterone; pharmaceutical formulation:
brexanolone) is a neurosteroid that has recently been approved for the treatment of …

Allopregnanolone (Allo), a neurosteroid, has emerged as a promising promoter of
endogenous regeneration in brain. In a mouse model of Alzheimer's disease, Allo induced …

Mangosteen fruit has been used for various disorders, including pain. The effects of alpha‐
mangostin, the main component of mangosteen, on the neuropathic pain caused by chronic …

Progesterone, which acts as a neurosteroid in nervous system, has been shown to have
neuroprotective effects in different experiments in vitro and in vivo. Our previous study …