In 1975, tau protein was isolated as a microtubule-associated factor from the porcine brain.
In the previous year, a paired helical filament (PHF) protein had been identified in …

Dynamic gain and loss of synapses is fundamental to healthy brain function. While
Alzheimer's Disease (AD) treatment strategies have largely focussed on beta-amyloid and …

Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside
within distinct regions of the brain. This phenomenon was first described over 50 years ago …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
abnormal protein modification, inflammation and memory impairment. Aggregated amyloid …

Alzheimer's disease (AD) is an incurable and debilitating chronic progressive
neurodegenerative disorder which is the leading cause of dementia worldwide. AD is a …

Alcoholism is associated with brain damage and impaired cognitive functioning. The relative
contributions of different etiological factors, such as alcohol, thiamine deficiency and age …

It is now well established, at least in animal models, that exercise elicits potent pro-cognitive
and pro-neurogenic effects. Alzheimer's disease (AD) is one of the leading causes of …

Alzheimer disease (AD) is the most prevalent form of dementia among elderly people.
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …

Aging is associated with increased inflammation and reduced hippocampal neurogenesis,
which may in turn contribute to cognitive impairment. Taurine is a free amino acid found in …

Alzheimer's disease is a chronic neurodegenerative devastating disorder affecting a high
percentage of the population over 65 years of age and causing a relevant emotional, social …