Genetics and Epigenetics in Obesity: What Do We Know so Far?

M Keller, SIA Svensson, K Rohde-Zimmermann… - Current Obesity …, 2023 - Springer
Abstract Purpose of Review Enormous progress has been made in understanding the
genetic architecture of obesity and the correlation of epigenetic marks with obesity and …

[HTML][HTML] DNA methylation profile is a quantitative measure of biological aging in children

X Wu, W Chen, F Lin, Q Huang, J Zhong, H Gao… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
DNA methylation changes within the genome can be used to predict human age. However,
the existing biological age prediction models based on DNA methylation are predominantly …

[HTML][HTML] DNA methylation in genes of longevity-regulating pathways: association with obesity and metabolic complications

F Salas-Pérez, O Ramos-Lopez, ML Mansego… - Aging (albany …, 2019 - ncbi.nlm.nih.gov
Aging is the main risk factor for most chronic diseases. Epigenetic mechanisms, such as
DNA methylation (DNAm) plays a pivotal role in the regulation of physiological responses …

DNA methylation and type 2 diabetes: the use of mendelian randomization to assess causality

DL Juvinao-Quintero, MF Hivert, GC Sharp… - … genetic medicine reports, 2019 - Springer
Abstract Purpose of Review This review summarises recent advances in the field of
epigenetics in order to understand the aetiology of type 2 diabetes (T2D). Recent Findings …

DNA methylation during human adipogenesis and the impact of fructose

G Tini, V Varma, R Lombardo, GT Nolen, G Lefebvre… - Genes & Nutrition, 2020 - Springer
Background Increased adipogenesis and altered adipocyte function contribute to the
development of obesity and associated comorbidities. Fructose modified adipocyte …

Genomwide association studies on obesity: what can we learn from these studies

F Kronenberg, B Paulweber, C Lamina - Wiener Medizinische …, 2016 - Springer
The introduction of genome-wide association studies resulted in a tremendous increase in
the number of genes associated with obesity and related phenotypes (BMI, waist and waist …

Transcriptional regulation of hypothalamic energy balance genes

DJ Good - Textbook of Energy Balance, Neuropeptide Hormones …, 2018 - Springer
Within the postnatal human brain, there are at least 4627 expressed transcription factors
(Hawrylycz et al. 2012). These transcription factors are differentially expressed within the …

Genomweite Assoziationsstudien zu Adipositas und was wir daraus lernen

F Kronenberg, B Paulweber, C Lamina - Wiener Medizinische …, 2016 - infona.pl
Die Einführung genomweiter Assoziationsstudien (GWAS) führte zu einem sprunghaften
Anstieg der Anzahl von Genen, die mit Adipositas und zusammenhängenden Phänotypen …

DNA methylation in genes of longevity‐regulating pathways: association with obesity and metabolic complications

JL Santos, JA Martinez, JI Riezu-Boj, FI Milagro-Yoldi… - 2019 - dadun.unav.edu
Aging is the main risk factor for most chronic diseases. Epigenetic mechanisms, such as
DNA methylation (DNAm) plays a pivotal role in the regulation of physiological responses …