Transglutaminases (Tgases) are a widely distributed group of enzymes that catalyse the
post-translational modification of proteins by the formation of isopeptide bonds. This occurs …

Abstract Transglutaminase 2 (TG2) is an inducible transamidating acyltransferase that
catalyzes Ca 2+-dependent protein modifications. It acts as a G protein in transmembrane …

Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme catalyzing the crosslinking
between Gln and Lys residues and involved in various pathophysiological events. Besides …

Transglutaminase 2 (TG2 or tissue transglutaminase) is a highly complex multifunctional
protein that acts as transglutaminase, GTPase/ATPase, protein disulfide isomerase, and …

The combined effects of concentration and pH on the conformational states of bovine serum
albumin (BSA) are investigated by small-angle x-ray scattering. Serum albumins, at …

Proteinaceous aggregates containing α-synuclein represent a feature of neurodegenerative
disorders such as Parkinson's disease, dementia with Lewy bodies, and multiple system …

Transglutaminase 2 (TG2) in the extracellular matrix is largely inactive but is transiently
activated upon certain types of inflammation and cell injury. The enzymatic activity of …

Allosteric regulation is a fundamental mechanism of biological control. Here, we investigated
the allosteric mechanism by which GTP inhibits cross-linking activity of transglutaminase 2 …

Abstract Transglutaminase 2 (TG2) plays a vital role in stabilizing extracellular matrix (ECM)
proteins through enzymatic crosslinking during tissue growth, repair, and inflammation. TG2 …

Small molecules are difficult to directly detect using commercially available surface plasmon
resonance (SPR) instruments. This is because low molecular weight compounds do not …