Senescent cells: an emerging target for diseases of ageing

BG Childs, M Gluscevic, DJ Baker… - Nature reviews Drug …, 2017 - nature.com
Chronological age represents the single greatest risk factor for human disease. One
plausible explanation for this correlation is that mechanisms that drive ageing might also …

Effect of sirolimus on malignancy and survival after kidney transplantation: systematic review and meta-analysis of individual patient data

GA Knoll, MB Kokolo, R Mallick, A Beck… - Bmj, 2014 - bmj.com
Objective To examine risk of malignancy and death in patients with kidney transplant who
receive the immunosuppressive drug sirolimus. Design Systematic review and meta …

The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients

MR Costanzo, A Dipchand, R Starling… - The Journal of heart and …, 2010 - Elsevier
CHAIR: Costanzo MR: Midwest Heart Foundation, Lombard Illinois, USA TASK FORCE 1:
Dipchand A: Hospital for Sick Children, Toronto Ontario, Canada; Starling R: Cleveland …

Antiviral drug resistance of human cytomegalovirus

NS Lurain, S Chou - Clinical microbiology reviews, 2010 - Am Soc Microbiol
The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …

Renal association clinical practice guideline in post-operative care in the kidney transplant recipient

RJ Baker, PB Mark, RK Patel, KK Stevens, N Palmer - BMC nephrology, 2017 - Springer
These guidelines cover the care of patients from the period following kidney transplantation
until the transplant is no longer working or the patient dies. During the early phase …

Consensus recommendations for use of maintenance immunosuppression in solid organ transplantation: Endorsed by the American College of Clinical Pharmacy …

J Nelson, N Alvey, L Bowman, J Schulte… - … : The Journal of …, 2022 - Wiley Online Library
Advances in maintenance immunosuppression over the past three decades have improved
solid organ transplantation outcomes dramatically. Uninterrupted access to …

Norovirus gastroenteritis in immunocompromised patients

K Bok, KY Green - New England Journal of Medicine, 2012 - Mass Medical Soc
Norovirus Gastroenteritis in Immunocompromised Patients | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

PEComas: the past, the present and the future

G Martignoni, M Pea, D Reghellin, G Zamboni… - Virchows Archiv, 2008 - Springer
The perivascular epithelioid cell (PEC) is a cell type constantly present in a group of tumors
called PEComas. PEC expresses myogenic and melanocytic markers, such as HMB45 and …

Immunosuppressive therapy and malignancy in organ transplant recipients: a systematic review

A Gutierrez-Dalmau, JM Campistol - Drugs, 2007 - Springer
Post-transplant malignancy is recognised as being a major limitation to the success of solid
organ transplantation and it is currently considered one of the unavoidable costs of long …

[HTML][HTML] Mammalian Target of Rapamycin Complex 1 Activation Is Required for the Stimulation of Human Skeletal Muscle Protein Synthesis by Essential Amino Acids1 …

JM Dickinson, CS Fry, MJ Drummond… - The Journal of …, 2011 - Elsevier
The relationship between mammalian target of rapamycin complex 1 (mTORC1) signaling
and muscle protein synthesis during instances of amino acid surplus in humans is based …