Chaotropicity: a key factor in product tolerance of biofuel-producing microorganisms

JA Cray, A Stevenson, P Ball, SB Bankar… - Current opinion in …, 2015 - Elsevier
Highlights•Disruption of cellular macromolecules by alcohols limits biofuel fermentations.•
Lignocellulose hydrolysis also generates chaotropic inhibitors (vanillin, phenolics …

Engineering membrane and cell-wall programs for tolerance to toxic chemicals: Beyond solo genes

NR Sandoval, ET Papoutsakis - Current opinion in microbiology, 2016 - Elsevier
Highlights•Membrane disruption limits high titer production of biofuels and
biochemicals.•Strains evolved to have high tolerance maintain optimal membrane fluidity …

Engineering the biological conversion of methanol to specialty chemicals in Escherichia coli

WB Whitaker, JA Jones, RK Bennett, JE Gonzalez… - Metabolic …, 2017 - Elsevier
Methanol is an attractive substrate for biological production of chemicals and fuels.
Engineering methylotrophic Escherichia coli as a platform organism for converting methanol …

A review on ethanol tolerance mechanisms in yeast: Current knowledge in biotechnological applications and future directions

GR Sahana, B Balasubramanian, KS Joseph… - Process …, 2024 - Elsevier
Saccharomyces cerevisiae is one of the prominent strains in the brewing and bioethanol
industries and has been used for many industrial purposes for ages. Though the organism is …

Reprogramming cellular metabolism to increase the efficiency of microbial cell factories

Q Ding, L Liu - Critical Reviews in Biotechnology, 2024 - Taylor & Francis
Recent studies are increasingly focusing on advanced biotechnological tools, self-adjusting
smart microorganisms, and artificial intelligent networks, to engineer microorganisms with …

Systems-level understanding of ethanol-induced stresses and adaptation in E. coli

H Cao, D Wei, Y Yang, Y Shang, G Li, Y Zhou, Q Ma… - Scientific reports, 2017 - nature.com
Understanding ethanol-induced stresses and responses in biofuel-producing bacteria at
systems level has significant implications in engineering more efficient biofuel producers …

[HTML][HTML] Biodegradation of aromatic pollutants meets synthetic biology

L Xiang, G Li, L Wen, C Su, Y Liu, H Tang… - Synthetic and Systems …, 2021 - Elsevier
Ubiquitously distributed microorganisms are natural decomposers of environmental
pollutants. However, because of continuous generation of novel recalcitrant pollutants due …

Comparative analysis of high butanol tolerance and production in clostridia

P Patakova, J Kolek, K Sedlar, P Koscova… - Biotechnology …, 2018 - Elsevier
Abstract 2016, was the 100 years anniversary from launching of the first industrial acetone-
butanol-ethanol (ABE) microbial production process. Despite this long period and also …

Microbial physiological engineering increases the efficiency of microbial cell factories

H Liu, Y Qi, P Zhou, C Ye, C Gao… - Critical Reviews in …, 2021 - Taylor & Francis
Microbial cell factories provide vital platforms for the production of chemicals. Advanced
biotechnological toolboxes have been developed to enhance their efficiency. However …

Microbial cell factories in the bioeconomy era: from discovery to creation

X Yan, Q He, B Geng, S Yang - BioDesign Research, 2024 - spj.science.org
Microbial cell factories (MCFs) are extensively used to produce a wide array of bioproducts,
such as bioenergy, biochemical, food, nutrients, and pharmaceuticals, and have been …