Restricted and repetitive behaviors (RRBs) are a core feature of autism spectrum disorders.
They constitute a major barrier to learning and social adaptation, but research on their …

The quantity and quality of research into autism and related conditions have increased
dramatically in recent years. Consequently we selectively review key accomplishments and …

The psychopharmacology of depression is a field that has evolved rapidly in just under 5
decades. Early antidepressant medications—tricyclic antidepressants (TCAs) and …

BACKGROUND: Clinical trial data provide an approach to the investigation of the effects of
psychopharmacological agents, and psychiatric disorders themselves, on seizure threshold …

A family-based, cognitive behavioural treatment for anxiety in 47 children with comorbid
anxiety disorders and High Functioning Autism Spectrum Disorder (HFA) was evaluated …

The hypothesis explored in this review is that the high levels of serotonin in the blood seen
in some autistic children (the so-called hyperserotonemia of autism) may lead to some of the …

We report the analysis of 335 microsatellite markers genotyped in 110 multiplex families with
autism. All families include at least two" affected" siblings, at least one of whom has autism; …

Autism is a neurodevelopmental disorder of genetic origins, with a heritability of about 90%.
Autistic disorder is classed within the broad domain of pervasive developmental disorders …

Background No animal models of autism spectrum disorders (ASD) with good construct
validity are currently available; using genetic models of pathologies characterized by ASD …

This pilot study examined the efficacy and tolerability of olanzapine in the treatment of
children, adolescents, and adults with pervasive developmental disorders (PDDs). Eight …