The senescence-associated secretory phenotype and its physiological and pathological implications
Cellular senescence is a state of terminal growth arrest associated with the upregulation of
different cell cycle inhibitors, mainly p16 and p21, structural and metabolic alterations …
different cell cycle inhibitors, mainly p16 and p21, structural and metabolic alterations …
Cellular senescence and kidney aging
N Rex, A Melk, R Schmitt - Clinical Science, 2023 - portlandpress.com
Life expectancy is increasing worldwide, and by 2050 the proportion of the world's
population over 65 years of age is estimated to surpass 1.5 billion. Kidney aging is …
population over 65 years of age is estimated to surpass 1.5 billion. Kidney aging is …
Unraveling the association between major depressive disorder and senescent biomarkers in immune cells of older adults: a single-cell phenotypic analysis
EC Lorenzo, JE Figueroa, DA Demirci, F El-Tayyeb… - Frontiers in …, 2024 - frontiersin.org
Background: Little is known about the prevalence of cellular senescence among immune
cells (ie, immune cells expressing senescence markers, iSCs) nor is there a gold-standard …
cells (ie, immune cells expressing senescence markers, iSCs) nor is there a gold-standard …
Time‐series transcriptome reveals inflammatory signature in monocytes and neutrophils following acute heat exposure in mine rescuers
J Wen, L Wang, J Cheng, T Ma, Q Wen… - Physiological …, 2024 - Wiley Online Library
Occupational exposure to extreme high temperatures and the increasing global
temperatures necessitates a deeper understanding of the impact of heat exposure on …
temperatures necessitates a deeper understanding of the impact of heat exposure on …