OP Joffre, E Segura, A Savina… - Nature Reviews …, 2012 - nature.com
The presentation of exogenous antigens on MHC class I molecules, known as cross- presentation, is essential for the initiation of CD8+ T cell responses. In vivo, cross …
T cell recognition of antigen-presenting cells depends on their expression of a spectrum of peptides bound to major histocompatibility complex class I (MHC-I) and class II (MHC-II) …
V Racanelli, B Rehermann - Hepatology, 2006 - Wiley Online Library
The liver is a unique anatomical and immunological site in which antigen‐rich blood from the gastrointestinal tract is pressed through a network of sinusoids and scanned by antigen …
ES Trombetta, I Mellman - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract The conversion of exogenous and endogenous proteins into immunogenic peptides recognized by T lymphocytes involves a series of proteolytic and other enzymatic …
FM Cruz, A Chan, KL Rock - Seminars in immunology, 2023 - Elsevier
Phagocytes, particularly dendritic cells (DCs), generate peptide-major histocompatibility complex (MHC) I complexes from antigens they have collected from cells in tissues and …
JM Vyas, AG Van der Veen, HL Ploegh - Nature Reviews Immunology, 2008 - nature.com
The principal components of both MHC class I and class II antigen processing and presentation pathways are well known. In dendritic cells, these pathways are tightly …
A Alloatti, F Kotsias, JG Magalhaes… - Immunological …, 2016 - Wiley Online Library
As a population, dendritic cells (DC s) appear to be the best cross‐presenters of internalized antigens on major histocompatibility complex class I molecules in the mouse. To do this, DC …
RM Steinman, H Hemmi - From innate immunity to immunological memory, 2006 - Springer
The innate immune system provides many ways to quickly resist infection. The twobest- studieddefenses indendritic cells (DCs) are the productionof protective cytokines—like …
JA Villadangos, P Schnorrer - Nature Reviews Immunology, 2007 - nature.com
Dendritic cells (DCs) comprise several subsets, and their roles in the presentation of antigens derived from pathogens, vaccines and self tissues are now beginning to be …