The mood stabilizers lithium and valproic acid (VPA) are traditionally used to treat bipolar
disorder (BD), a severe mental illness arising from complex interactions between genes and …

Transplantation of bone marrow-derived mesenchymal stromal cells (MSCs) into the injured
brain or spinal cord may provide therapeutic benefit. Several models of central nervous …

NeuN (neuronal nuclei) is a neuron-specific nuclear protein which is identified by
immunoreactivity with a monoclonal antibody, anti-NeuN. Anti-NeuN has been used widely …

Transplantation of bone marrow stem cells into spinal cord lesions enhances axonal
regeneration and promotes functional recovery in animal studies. There are two types of …

The ability of stem/progenitor cells to migrate and engraft into host tissues is key to their
potential use in gene and cell therapy. Among the cells of interest are the adherent cells …

Nowadays, the research on NPC transplantation in neurological disorders is advancing on
two different fronts: on one hand, recent preclinical data are uncovering the molecular basis …

We have investigated the phenotypic and bioassay characteristics of bone marrow
mesenchymal stromal cells (MSCs) differentiated along a Schwann cell lineage using glial …

Background—Hematopoietic cytokines, granulocyte colony-stimulating factor (G-CSF), and
stem cell factor (SCF) were reported to show a neuroprotective effect or to support …

Although stem cell-based treatments for stroke and other neurodegenerative diseases have
advanced rapidly, there are still few clinical treatments available. In this study, rats receiving …

Abstract Spinal Cord Injury (SCI) is a serious devastating condition associated to the high
chances of morbidity and mortality. It involves a primary and a secondary injury, former …