Drug resistance mechanisms in helminths: is it survival of the fittest?
CE James, AL Hudson, MW Davey - Trends in parasitology, 2009 - cell.com
Development of resistance to anthelmintic drugs is an increasing problem that decreases
the productivity of livestock and threatens the success of treatment in humans. It is essential …
the productivity of livestock and threatens the success of treatment in humans. It is essential …
Clinical isolates of uncomplicated falciparum malaria from high and low malaria transmission areas show distinct pfcrt and pfmdr1 polymorphisms in western …
G Tadele, A Jawara, M Oboh, E Oriero, S Dugassa… - Malaria Journal, 2023 - Springer
Background Pfcrt gene has been associated with chloroquine resistance and the pfmdr1
gene can alter malaria parasite susceptibility to lumefantrine, mefloquine, and chloroquine …
gene can alter malaria parasite susceptibility to lumefantrine, mefloquine, and chloroquine …
[HTML][HTML] Distribution of drug resistance genotypes in Plasmodium falciparum in an area of limited parasite diversity in Saudi Arabia
SMB Dajem, HM Al-Farsi, ZS Al-Hashami… - The American journal …, 2012 - ncbi.nlm.nih.gov
Two hundred and three Plasmodium falciparum isolates from Jazan area, southwest Saudi
Arabia, were typed for Pfcrt, Pfmdr1, dhps, and dhfr mutations associated with resistance to …
Arabia, were typed for Pfcrt, Pfmdr1, dhps, and dhfr mutations associated with resistance to …
Analysis of gene mutations involved in chloroquine resistance in Plasmodium falciparum parasites isolated from patients in the southwest of Saudi Arabia
SM Bin Dajem, A Al-Qahtani - Annals of Saudi medicine, 2010 - annsaudimed.net
BACKGROUND AND OBJECTIVES: Chloroquine has been the drug of choice for the
treatment of malaria for many decades. We aimed to examine the molecular basis of …
treatment of malaria for many decades. We aimed to examine the molecular basis of …
Polymorphism analysis of pfmdr1 gene in Plasmodium falciparum isolates 11 years post-adoption of artemisinin-based combination therapy in Saudi Arabia
A total of 227 Plasmodium falciparum isolates from Jazan region, southwestern Saudi
Arabia were amplified for the P. falciparum multi-drug resistance 1 (pfmdr1) gene to detect …
Arabia were amplified for the P. falciparum multi-drug resistance 1 (pfmdr1) gene to detect …
Source of drug resistant Plasmodium falciparum in a potential malaria elimination site in Saudi Arabia
HM Al-Farsi, ZS Al-Hashami, SMB Dajem… - Infection, Genetics and …, 2012 - Elsevier
A major challenge to the success of malaria control program in Saudi Arabia is the high
influx of expatriates and holy visitors from malaria endemic countries. In the present study …
influx of expatriates and holy visitors from malaria endemic countries. In the present study …
[HTML][HTML] Simple molecular methods for early detection of chloroquine drug resistance in Plasmodium vivax and Plasmodium falciparum
G Singh, R Singh, AD Urhehar - Journal of clinical and diagnostic …, 2016 - ncbi.nlm.nih.gov
Aim To standardize chloroquine drug sensitivity testing by molecular method so as to
provide reports of chloroquine within 6-8 hours to physicians for better treatment. Materials …
provide reports of chloroquine within 6-8 hours to physicians for better treatment. Materials …
[PDF][PDF] Current prevalence of falciparum malarial infection among HIV patients on highly active antiretroviral therapy in University of Uyo teaching Hospital, Uyo …
CP Amadi, GM Ikon, UC Inyang - Int J Res Med Sci, 2018 - academia.edu
Background: Malaria and HIV remain two leading causes of morbidity and mortality to
patients in developing African countries. Both infectious diseases have been documented to …
patients in developing African countries. Both infectious diseases have been documented to …
[HTML][HTML] The role of molecular techniques on Malaria control and elimination programs in Iran: A review article
S Gholizadeh, NN Karimi, S Zakeri… - Iranian Journal of …, 2018 - ncbi.nlm.nih.gov
Background: The aim of this review was to describe the application of molecular methods in
epidemiological aspects of malaria vectors, parasites, and human hosts in Iran and their …
epidemiological aspects of malaria vectors, parasites, and human hosts in Iran and their …
[HTML][HTML] The drug resistance of plasmodium falciparum and P. vivax in Iran: a review article
A Heidari, H Keshavarz - Iranian Journal of Parasitology, 2021 - ncbi.nlm.nih.gov
Background: One of the main obstacles to malaria control in the world has been the
emergence of resistance in Plasmodium falciparum to chloroquine and other anti-malarial …
emergence of resistance in Plasmodium falciparum to chloroquine and other anti-malarial …