Using machine learning approach for screening metastatic biomarkers in colorectal cancer and predictive modeling with experimental validation
Colorectal cancer (CRC) liver metastasis accounts for the majority of fatalities associated
with CRC. Early detection of metastasis is crucial for improving patient outcomes but can be …
with CRC. Early detection of metastasis is crucial for improving patient outcomes but can be …
TNF‐α can promote membrane invasion by activating the MAPK/MMP9 signaling pathway through autocrine in bone‐invasive pituitary adenoma
X Wu, L Gong, B Li, J Bai, C Li… - CNS Neuroscience & …, 2024 - Wiley Online Library
Aims A bone‐invasive pituitary adenoma exhibits aggressive behavior, leading to a worse
prognosis. We have found that TNF‐α promotes bone invasion by facilitating the …
prognosis. We have found that TNF‐α promotes bone invasion by facilitating the …
Repurposing denosumab in lung cancer beyond counteracting the skeletal related events: an intriguing perspective
MV Deligiorgi, DT Trafalis - Expert Opinion on Biological Therapy, 2020 - Taylor & Francis
Introduction Repurposing denosumab in lung cancer therapeutics capitalizes on its well-
established role in preventing the skeletal related events (SREs) and its emerging, yet …
established role in preventing the skeletal related events (SREs) and its emerging, yet …
The Hoof Color of Australian White Sheep Is Associated with Genetic Variation of the MITF Gene
P Su, H Wu, Y Huang, X Lu, J Yin, Q Zhang, X Lan - Animals, 2023 - mdpi.com
Simple Summary In this research, we used RAD-seq genotyping data and GWAS to identify
SNPs in the MITF gene that were significantly associated with hoof color in the Australian …
SNPs in the MITF gene that were significantly associated with hoof color in the Australian …
Association of Genetic Polymorphisms in TNFRSF11 with the Progression of Genetic Susceptibility to Gastric Cancer
Y Fan, X Gu, H Pan, Z Dai, C Zou, Z Gao… - Journal of …, 2020 - Wiley Online Library
Objective. To investigate the relationship between polymorphism of TNFRSF11 gene
rs9533156 and rs2277438 and susceptibility to gastric cancer. Methods. A case‐control …
rs9533156 and rs2277438 and susceptibility to gastric cancer. Methods. A case‐control …
Patient-specific cell communication networks associate with disease progression in cancer
The maintenance and function of tissues in health and disease depends on cell–cell
communication. This work shows how high-level features, representing cell–cell …
communication. This work shows how high-level features, representing cell–cell …
Identifying metastatic biomarkers of colorectal cancer: Machine learning modeling and experimental validation
A Ahmadieh-Yazdi, A Mahdavinezhad, L Tapak… - 2023 - researchsquare.com
Background Colorectal cancer (CRC) liver metastasis is responsible for the majority of CRC-
related deaths. Early detection of metastasis is crucial for improving patient outcomes but …
related deaths. Early detection of metastasis is crucial for improving patient outcomes but …
Le métabolisme mitochondrial: un facteur clé dans la survie des cellules cancéreuses sous traitements anticancéreux
A Trinh - 2019 - theses.hal.science
De nombreux arguments indiquent que les cellules cancéreuses présentent une glycolyse
exacerbée quelle que soit la teneur en oxygène, un phénomène appelé «Effet Warburg» ou …
exacerbée quelle que soit la teneur en oxygène, un phénomène appelé «Effet Warburg» ou …