Axial spondyloarthritis (axSpA) encompasses both radiographic and non-radiographic
axSpA. It is a chronic inflammatory disease with a predilection for involving the axial …

Monoclonal antibodies (mAbs) have become one of the most important classes of
biopharmaceutical products, and they continue to dominate the universe of …

Summary Background Upadacitinib, a Janus kinase inhibitor, has been shown to be
effective in patients with ankylosing spondylitis. We aimed to assess the efficacy and safety …

Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema.
It impairs patients' quality of life enormously. It has been recognized not only as a skin …

Objective To update the evidence on efficacy and safety of biological disease-modifying
antirheumatic drugs (bDMARDs) in patients with axial spondyloarthritis (axSpA) to inform the …

Since the late 1990s, tumor necrosis factor alpha (TNF-α) inhibitors (anti-TNFs) have
revolutionized the therapy of immune-mediated inflammatory diseases (IMIDs) affecting the …

The complex crosstalk between the immune and the skeletal systems plays an
indispensable role in the maintenance of skeletal homeostasis. Various cytokines are …

Abstract Background Upadacitinib, a Janus kinase inhibitor, has demonstrated efficacy and
an acceptable safety profile in patients with ankylosing spondylitis (AS) in the phase III …

Psoriasis is an immune-mediated inflammatory skin disease associated with numerous
inflammatory comorbidities, including increased cardiovascular risk. The interleukin (IL) …

Axial spondyloarthritis (axial-SpA) is a multifactorial disease characterized by inflammation
in sacroiliac joints and spine, bone reabsorption, and aberrant bone deposition, which may …