Penetration of antibiotics into subcutaneous and intramuscular interstitial fluid: a meta-analysis of microdialysis studies in adults

PJ De Sutter, E Hermans, P De Cock… - Clinical …, 2024 - Springer
Abstract Background and Objective The interstitial fluid of tissues is the effect site for
antibiotics targeting extracellular pathogens. Microdialysis studies investigating these …

Have We Neglected to Study Target-Site Drug Exposure in Children? A Systematic Review of the Literature

E Hermans, J Meersschaut, I Van Herteryck… - Clinical …, 2024 - Springer
Abstract Background and Objective Drug dosing should ideally be based on the drug
concentrations at the target site, which, for most drugs, corresponds to the tissue. The exact …

[HTML][HTML] The Preparation and Evaluation of a Hydrochloride Hydrogel Patch with an Iontophoresis-Assisted Release of Terbinafine for Transdermal Delivery

M Li, X Chen, X Su, W Gao - Gels, 2024 - mdpi.com
Background: Terbinafine hydrochloride (TEB) is a broad-spectrum antifungal medication
commonly used to treat fungal infections of the skin. This study designed a hydrogel patch …