Lipid droplets: packing hydrophobic molecules within the aqueous cytoplasm

A Guzha, P Whitehead, T Ischebeck… - Annual review of …, 2023 - annualreviews.org
Lipid droplets, also known as oil bodies or lipid bodies, are plant organelles that
compartmentalize neutral lipids as a hydrophobic matrix covered by proteins embedded in a …

Subcellular compartmentalization in the biosynthesis and engineering of plant natural produces

L Yao, X Wu, X Jiang, M Shan, Z Zhang, Y Li… - Biotechnology …, 2023 - Elsevier
Plant natural products (PNPs) are specialized metabolites with diverse bioactivities. They
are extensively used in the pharmaceutical, cosmeceutical and food industries. PNPs are …

Metabolic engineering of Yarrowia Lipolytica for high-level production of squalene

Z Liu, M Huang, H Chen, X Lu, Y Tian, P Hu… - Bioresource …, 2024 - Elsevier
Squalene is an important triterpene with a wide range of applications. Given the growing
market demand for squalene, the development of microbial cell factories capable of …

Fabrication techniques of biomimetic scaffolds in three‐dimensional cell culture: A review

AK Badekila, S Kini, AK Jaiswal - Journal of cellular physiology, 2021 - Wiley Online Library
In the last four decades, several researchers worldwide have routinely and meticulously
exercised cell culture experiments in two‐dimensional (2D) platforms. Using traditionally …

Making small molecules in plants: a chassis for synthetic biology‐based production of plant natural products

X Liu, P Zhang, Q Zhao… - Journal of Integrative Plant …, 2023 - Wiley Online Library
Plant natural products have been extensively exploited in food, medicine, flavor, cosmetic,
renewable fuel, and other industrial sectors. Synthetic biology has recently emerged as a …

Engineering a universal and efficient platform for terpenoid synthesis in yeast

Y Ma, Y Zu, S Huang… - Proceedings of the …, 2023 - National Acad Sciences
Engineering microbes for the production of valuable natural products is often hindered by
the regulation of native competing metabolic networks in host. This is particularly evident in …

Lipid droplets throughout the evolutionary tree

PK Lundquist, KK Shivaiah… - Progress in Lipid Research, 2020 - Elsevier
Intracellular lipid droplets are utilized for lipid storage and metabolism in organisms as
evolutionarily diverse as animals, fungi, plants, bacteria, and archaea. These lipid droplets …

A glossary of plant cell structures: current insights and future questions

BH Kang, CT Anderson, S Arimura, E Bayer… - The Plant …, 2022 - academic.oup.com
In this glossary of plant cell structures, we asked experts to summarize a present-day view of
plant organelles and structures, including a discussion of outstanding questions. In the …

New frontiers: harnessing pivotal advances in microbial engineering for the biosynthesis of plant-derived terpenoids

MS Belcher, J Mahinthakumar, JD Keasling - Current opinion in …, 2020 - Elsevier
Highlights•Terpenoids are a vast and diverse class of compounds with applications in both
the industrial and human health spaces.•Computational biology and gene discovery enable …

Subcellular engineering of lipase dependent pathways directed towards lipid related organelles for highly effectively compartmentalized biosynthesis of triacylglycerol …

K Yang, Y Qiao, F Li, Y Xu, Y Yan, C Madzak… - Metabolic engineering, 2019 - Elsevier
As an alternative to in vitro lipase dependent biotransformation and to traditional assembly
of pathways in cytoplasm, the present study focused on targeting lipase dependent …