The generation of reactive oxygen species (ROS) and an imbalance of antioxidant defence
mechanisms can result in oxidative stress. Several pro-atherogenic stimuli that promote …

The advances in biotechnology, biomechanics, and biomaterials can be used to develop
organ models that aim to accurately emulate their natural counterparts. Heart disease, one …

The commercial polydimethysiloxane elastomer Sylgard® 184 with mixing ratio 10: 1 is in
wide use for biomedical research or fundamental studies of mechanobiology. In this paper, a …

Human mesenchymal stem cells (hMSCs) have emerged as an important cell type in cell
therapy and tissue engineering. In these applications, maintaining the therapeutic properties …

Mesenchymal stem cells (MSCs) are an appealing potential therapy for vascular diseases;
however, many challenges remain in their clinical translation. While the use of biochemical …

Substrate stiffness and topography are two powerful means by which mesenchymal stem
cells (MSCs) activities can be modulated. The effects of substrate stiffness on the MSCs …

Recurrence of intervertebral disc (IVD) herniation is the most important factor leading to
chronic low back pain and subsequent disability after discectomy. Efficacious annulus …

Mesenchymal stem cells (MSCs) are the common precursors of several functionally
disparate cell lineages. A plethora of chemical and physical stimuli contribute to lineage …

Cell culture is a core and basic technique in biotechnology and is widely applied in biology,
medicine, drug research and development. Traditional two-dimensional cell culture methods …

Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into any
mesenchymal tissue, including bone, cartilage, muscle, and fat. MSC differentiation can be …