Intricate 3D architecture of a DNA mimic of GFP

LFM Passalacqua, MT Banco, JD Moon, X Li… - Nature, 2023 - nature.com
Numerous studies have shown how RNA molecules can adopt elaborate three-dimensional
(3D) architectures,–. By contrast, whether DNA can self-assemble into complex 3D folds …

Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture

LFM Passalacqua, MR Starich, KA Link, J Wu… - Nature …, 2023 - nature.com
Beetroot is a homodimeric in vitro selected RNA that binds and activates DFAME, a
conditional fluorophore derived from GFP. It is 70% sequence-identical to the previously …

Construction of a self-priming hairpin probe for rapid and isothermally one-step detection of multiple long noncoding RNAs in living cells and tissues

X Liu, Y Han, S Wei, B Zhou, X Zou, C Zhang - Chemical Engineering …, 2025 - Elsevier
Long noncoding RNAs (lncRNAs) serve as important regulators and therapeutic targets in
numerous biological and disease-related processes, and their dysregulated expression may …

[HTML][HTML] Biophysical characterization and design of a minimal version of the Hoechst RNA aptamer

NM Evans, LR Shivers, AJ To, GK Murphy… - Biochemical and …, 2024 - Elsevier
RNA aptamers are oligonucleotides, selected through Systematic Evolution of Ligands by
EXponential Enrichment (SELEX), that can bind to specific target molecules with high …

Engineering light-inducible transcription factors for control of gene expression

S Royo Miguel - 2024 - orca.cardiff.ac.uk
Light-oxygen-voltage (LOV) photoreceptors are ubiquitous blue light sensing domains that
regulate the activity of various effectors, such as DNA binding domains. Illumination of a LOV …

[PDF][PDF] Biochemical Characterization and Optimization of RNA Aptamers Bound to Hoechst Dye Derivatives

N Evans - 2023 - uwspace.uwaterloo.ca
Ribonucleic acid (RNA) aptamers are single-stranded nucleic acids that are typically
selected through a process known as Systematic Evolution of Ligands by EXponential …