Therapeutic potential of neurotrophic factors in Alzheimer's Disease

A Nasrolahi, F Javaherforooshzadeh… - Molecular biology …, 2022 - Springer
Introduction Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the
most common cause of dementia among the elderly population. AD is accompanied with the …

Bridging neurotrophic factors and bioactive peptides to Alzheimer's disease

M Wei, T Wu, N Chen - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder. As the demographic shifting
towards an aging population, AD has emerged as a prominent public health concern. The …

Exploring small non-coding RNAs as blood-based biomarkers to predict Alzheimer's disease

L Gutierrez-Tordera, C Papandreou, N Novau-Ferré… - Cell & Bioscience, 2024 - Springer
Background Alzheimer's disease (AD) diagnosis relies on clinical symptoms complemented
with biological biomarkers, the Amyloid Tau Neurodegeneration (ATN) framework. Small …

Integrated analysis of the chemical-material basis and molecular mechanisms for the classic herbal formula of Lily Bulb and Rehmannia Decoction in alleviating …

H Zhang, X Xue, J Pan, X Song, X Chang, Q Mao… - Chinese medicine, 2021 - Springer
Abstract Background Lily Bulb and Rehmannia Decoction (LBRD), is a traditional Chinese
formula that has been shown to be safe and effective against depression; however, its …

Identification of peripheral blood miRNA biomarkers in first-episode drug-free schizophrenia patients using bioinformatics strategy

M Jin, X Zhu, Y Sun, Z Li, X Li, L Ai, Y He, Y Liu… - Molecular …, 2022 - Springer
Schizophrenia (SCZ) is a polygenic, complex mental disorder of which a diagnosis is often
made based on psychiatric history and clinical observation with few available objectives and …

Dysfunctional microRNA-144-3p/ZBTB20/ERK/CREB1 signalling pathway is associated with MK-801-induced schizophrenia-like abnormalities

B Pan, B Han, X Zhu, Y Wang, H Ji, J Weng, Y Liu - Brain Research, 2023 - Elsevier
Schizophrenia is a group of severe mental disorders. ZBTB20 is critical in brain
development and corticogenesis and its dysfunction induces various neural disorders …

Baihe Dihuang (Lilium Henryi Baker and Rehmannia Glutinosa) decoction attenuates somatostatin interneurons deficits in prefrontal cortex of depression via miRNA …

X Xue, J Pan, H Zhang, Y Lu, Q Mao, K Ma - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Baihe Dihuang Decoction is a well-known
traditional Chinese medicine prescription (Also known as Lilium Henryi Baker and …

REGULATORY ROLES OF microRNAs IN MODULATING MITOCHONDRIAL DYNAMICS, AMYLOID BETA FIBRILLATION, MICROGLIAL ACTIVATION, AND …

M Sharma, AK Tanwar, PK Purohit, P Pal… - Neuroscience & …, 2024 - Elsevier
Alzheimer's Disease (AD) remains a formidable challenge due to its complex pathology,
notably involving mitochondrial dysfunction and dysregulated microRNA (miRNA) signaling …

Effects of icariin on alleviating schizophrenia-like symptoms by regulating the miR-144-3p/ATP1B2/mTOR signalling pathway

B Pan, L Xu, J Weng, Y Wang, H Ji, B Han, X Zhu… - Neuroscience …, 2022 - Elsevier
Schizophrenia is a group of severe mental disorders. Icariin is a main active component of
Epimedium, possessing therapeutic effects on various neurodegenerative diseases. The …

A review of miRNAs as biomarkers and effect of dietary modulation in obesity associated cognitive decline and neurodegenerative disorders

M Perdoncin, A Konrad, JR Wyner, S Lohana… - Frontiers in Molecular …, 2021 - frontiersin.org
There has been a progressive increase in the prevalence of obesity and its comorbidities
such as type 2 diabetes and cardiovascular diseases worldwide. Recent studies have …