Thyroid function affects multiple sites of the female hypothalamic-pituitary gonadal (HPG)
axis. Disruption of thyroid function has been linked to reproductive dysfunction in women …

The narrow standard age range of menopause,∼ 50 yr, belies the complex balance of
forces that govern the underlying formation and progressive loss of ovarian follicles (the …

Objective: The aim of the study was to investigate the relationship between premature
ovarian failure and autoimmune disease. Methods: This interdisciplinary prospective study …

Purpose of review To describe the immunological mechanism in the pathogenesis of
premature ovarian insufficiency (POI), summarize the alternations in humoral immunity and …

Background Evidence suggests that hypothyroidism and thyroid autoimmunity (TAI) are
possibly associated with ovarian dysfunction. This meta‐analysis aimed to investigate …

OBJECTIVE: To investigate the therapeutic effect of Er-Xian decoction (二仙汤, EXD) on the
autoimmune premature ovarian failure (POF) in mice, and its regulatory mechanisms …

Background The human ovary is the target of autoimmune attack in cases of autoimmune
disorders, which can cause ovarian dysfunction. Due to the higher prevalence of …

Abstract Objective Currently, whether Hashimoto's thyroiditis decreases ovarian reserve is
not clearly known, given the conflicting findings from previous studies. This study was …

Objective Autoimmunity seems to be present in a large proportion of women with
spontaneous premature ovarian insufficiency (POI). Whether these women are at increased …

Background: Thyroid autoimmunity (TAI) is the most frequent autoimmune disease among
reproductive-aged women. It has been related to premature ovarian insufficiency, but the …