Chimeric vaccine design against the conserved TonB-dependent receptor-like β-barrel domain from the outer membrane tbpA and hpuB proteins of Kingella kingae …

MM Mashraqi, A Alzamami, NA Alturki… - Frontiers in Molecular …, 2023 - frontiersin.org
Kingella kingae is a Gram-negative bacterium that primarily causes pediatric infections such
as septicemia, endocarditis, and osteoarticular infections. Its virulence is attributed to the …

Inhibiting heme-piracy by pathogenic Escherichia coli using de novo-designed proteins

DR Fox, K Asadollahi, IG Samuels, B Spicer, A Kropp… - bioRxiv, 2024 - biorxiv.org
Iron is an essential nutrient for most bacteria and is often growth-limiting during infection,
due to the host sequestering free iron as part of the innate immune response. To obtain the …

Shigellosis: The Road from Multiple Drug-Resistance (MDR) to Vaccine Development

CH Leow, A Kazi, C Chuah, Z Xu, KKB Singh… - Integrated Science for …, 2024 - Springer
In regions facing development challenges, bacillary dysentery stands out as a prevalent
diarrheal infection, particularly endemic in temperate and tropical climates. Shigellosis, as …