Within the past four decades, the efforts of investigators worldwide have established the
amino acid homocysteine (Hcy) as an important factor in arteriosclerosis and ageing. The …

Background: Folic aid plays an essential role in cellular metabolism. Its deficiency can lead
to neural tube defects. However, optimization of body folate homeostasis can reduce the …

OBJECTIVE: We evaluated the effects of folic acid on homocysteine levels and oxidative
stress in 46 stable patients on hemodialysis. METHODS: This double-blind, placebo …

Folic acid plays an important role in cellular metabolic activities. The present study was
designed to investigate the protective effect of folic acid against lead acetate-induced …

This study carried out a 10-week feeding trial to investigate the effects of dietary folic acid on
the growth, digestive enzyme activity, immune response and antioxidant enzyme activity of …

Folate ingestion below and above the physiologic dose has been shown to play a
tumorigenic role in certain cancers. Also, excessive folate supplementation after …

Epidemiologic and experimental studies showed that folate deficiency is associated with
increased risk of degenerative diseases by enhancing abnormal one-carbon metabolism …

The present study evaluated the role of dietary folate modulations in the development of
hepatocellular carcinoma (HCC) in a rat model. Male Wistar rats were given …

Azathioprine (Aza) is an important drug commonly used in the therapy of autoimmune
system disorders. It induces hepatotoxicity and hazard effects that restrict its use. The effects …

The present study evaluated the effects of 5-methyltetrahydrofolate (5-MTHF) and Spirulina
aqueous extract on diabetes. An in silico docking study with select Spirulina bioactive …