[HTML][HTML] Therapeutic vaccines for high-risk HPV-associated diseases

A Chabeda, RJR Yanez, R Lamprecht, AE Meyers… - Papillomavirus …, 2018 - Elsevier
Cancer is the second leading cause of death worldwide, and it is estimated that Human
papillomavirus (HPV) related cancers account for 5% of all human cancers. Current HPV …

Emergence of novel coronavirus 2019-nCoV: need for rapid vaccine and biologics development

B Shanmugaraj, A Malla, W Phoolcharoen - Pathogens, 2020 - mdpi.com
Novel Coronavirus (2019-nCoV) is an emerging pathogen that was first identified in Wuhan,
China in late December 2019. This virus is responsible for the ongoing outbreak that causes …

Virus-like particles as preventive and therapeutic cancer vaccines

AL Tornesello, M Tagliamonte, FM Buonaguro… - Vaccines, 2022 - mdpi.com
Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …

Plant-based vaccines against viruses

EP Rybicki - Virology journal, 2014 - Springer
Plant-made or “biofarmed” viral vaccines are some of the earliest products of the technology
of plant molecular farming, and remain some of the brightest prospects for the success of this …

Plant‐made oral vaccines against human infectious diseases—are we there yet?

HT Chan, H Daniell - Plant biotechnology journal, 2015 - Wiley Online Library
Although the plant‐made vaccine field started three decades ago with the promise of
developing low‐cost vaccines to prevent infectious disease outbreaks and epidemics …

Peptide-based nanovaccines in the treatment of cervical cancer: a review of recent advances

J Zhang, J Fan, M Skwarczynski… - International Journal …, 2022 - Taylor & Francis
Persistent infection with high-risk human papillomaviruses (HPVs), such as HPV-16 and
HPV-18, can induce cervical cancer in humans. The disease carries high morbidity and …

Clinical significance of peripheral blood and tumor tissue lymphocyte subsets in cervical cancer patients

Y Wu, S Ye, S Goswami, X Pei, L Xiang, X Zhang… - BMC cancer, 2020 - Springer
Background Alterations in peripheral blood lymphocytes in cervical cancer have been
reported, although conflicting views exist. The present study investigated the distributions of …

Using transgenic plants and modified plant viruses for the development of treatments for human diseases

HS Loh, BJ Green, V Yusibov - Current opinion in virology, 2017 - Elsevier
Highlights•Concept of plant-based biofactories for therapeutics and biologics.•Industrial
preference of transient expression system—agroinfiltration.•Advancement of virus-like …

Harnessing the potential of plant expression system towards the production of vaccines for the prevention of human papillomavirus and cervical cancer

B Shanmugaraj, A Malla, CJI Bulaon, W Phoolcharoen… - Vaccines, 2022 - mdpi.com
Cervical cancer is the most common gynecological malignant tumor worldwide, and it
remains a major health problem among women, especially in developing countries. Despite …

Virus‐based nanoparticles as platform technologies for modern vaccines

KL Lee, RM Twyman, S Fiering… - Wiley Interdisciplinary …, 2016 - Wiley Online Library
Nanoscale engineering is revolutionizing the development of vaccines and
immunotherapies. Viruses have played a key role in this field because they can function as …