Cancer of the pancreas remains one of the deadliest cancer types. Based on the
GLOBOCAN 2012 estimates, pancreatic cancer causes more than 331000 deaths per year …

Pancreatic cancers arise predominantly from ductal epithelial cells of the exocrine pancreas
and are of the ductal adenocarcinoma histological subtype (PDAC). PDAC is an aggressive …

Pancreatic ductal adenocarcinomas (PDACs) are highly metastatic with poor prognosis,
mainly due to delayed detection. We hypothesized that intercellular communication is critical …

Background: The neutrophil-lymphocyte ratio (NLR) has been proposed as an indicator of
systemic inflammatory response. Previous findings from small-scale studies revealed …

Abstract Background Pancreatic neuroendocrine tumors (PNETs) are uncommon
neoplasms that can present with symptoms of hormone overproduction. We evaluated the …

Kupffer cells are resident liver macrophages and play a critical role in maintaining liver
functions. Under physiological conditions, they are the first innate immune cells and protect …

Objective: To explore the prognostic importance and preoperative predictors of lymph node
metastasis in an effort to guide surgical decision making in patients with pancreatic …

Pancreatic endocrine neoplasms (PETs) are uncommon tumors with an annual incidence
less than 1 per 100,000 persons per year in the general population. PETs that produce …

Purpose The American Joint Committee on Cancer (AJCC) staging manual (seventh edition)
has introduced its first TNM staging classification for pancreatic neuroendocrine tumors …

Background: Pancreatic neuroendocrine tumors (PNET) have a poorly defined natural
history, and a staging system is not available. The objective of this study was to identify …