Oligosaccharide analysis by mass spectrometry: a review of recent developments

MJ Kailemia, LR Ruhaak, CB Lebrilla… - Analytical …, 2014 - ACS Publications
Carbohydrates are central players in a number of important biological processes including
cell signaling, cell adhesion, and the regulation of biochemical pathways. Unlike nucleic …

Chromatographic, electrophoretic, and mass spectrometric methods for the analytical characterization of protein biopharmaceuticals

S Fekete, D Guillarme, P Sandra, K Sandra - Analytical Chemistry, 2016 - ACS Publications
Protein biopharmaceuticals are macromolecules with a therapeutic effect, commonly
produced by the recombinant DNA technology. They have emerged as important …

Orthogonal liquid chromatography–mass spectrometry methods for the comprehensive characterization of therapeutic glycoproteins, from released glycans to intact …

E Largy, F Cantais, G Van Vyncht, A Beck… - … of Chromatography A, 2017 - Elsevier
Proteins are increasingly used as therapeutics. Their characterization is challenging due to
their size and inherent heterogeneity notably caused by post-translational modifications …

Mass spectrometry for protein sialoglycosylation

Q Zhang, Z Li, Y Wang, Q Zheng… - Mass Spectrometry …, 2018 - Wiley Online Library
Sialic acids are a family of structurally unique and negatively charged nine‐carbon sugars,
normally found at the terminal positions of glycan chains on glycoproteins and glycolipids …

From mass spectrometry-based glycosylation analysis to glycomics and glycoproteomics

KH Khoo - Glycobiology of the Nervous System, 2014 - Springer
Mass spectrometry (MS) is the pivotal technique driving most current day protein
glycosylation analysis. It is unrivaled in combining high sensitivity, resolution, and precision …

[图书][B] Studies on O-glycosylation of Mucin-Type Proteins and Their Binding to Antibodies, Bacterial Toxins and Viral Receptors

S Gaunitz - 2013 - search.proquest.com
Carbohydrates are ubiquitous on the surface of all cells in mammals where they are
involved in interactions with the surroundings (extracellular matrix), other cells (including self …

[PDF][PDF] STUDIES ON O-GLYCOSYLATION OF MUCIN-TYPE PROTEINS AND THEIR BINDING TO ANTIBODIES, BACTERIAL

S GAUNITZ - 2013 - core.ac.uk
Carbohydrates are ubiquitous on the surface of all cells in mammals where they are
involved in interactions with the surroundings (extracellular matrix), other cells (including self …

[引用][C] Orthogonal LC/MS methods for the comprehensive characterization of therapeutic glycoproteins, from released glycans to intact protein level

AE Largy, F Cantais, V Vyncht, A Delobel, V Vyncht… - J. Chromatogr. A, 2017