Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds
HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
Flavonols and flavones as potential anti‐inflammatory, antioxidant, and antibacterial compounds
MSS Chagas, MD Behrens… - Oxidative medicine …, 2022 - Wiley Online Library
Plant preparations have been used to treat various diseases and discussed for centuries.
Research has advanced to discover and identify the plant components with beneficial effects …
Research has advanced to discover and identify the plant components with beneficial effects …
The E-cadherin and N-cadherin switch in epithelial-to-mesenchymal transition: signaling, therapeutic implications, and challenges
Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis
where the EMT program enhances metastasis, chemoresistance and tumor stemness. Due …
where the EMT program enhances metastasis, chemoresistance and tumor stemness. Due …
[HTML][HTML] Luteolin, a flavonoid, as an anticancer agent: A review
Many food-derived phytochemicals and their derivatives represent a cornucopia of new anti-
cancer compounds. Luteolin (3, 4, 5, 7-tetrahydroxy flavone) is a flavonoid found in different …
cancer compounds. Luteolin (3, 4, 5, 7-tetrahydroxy flavone) is a flavonoid found in different …
Targeting AKT/mTOR in oral cancer: mechanisms and advances in clinical trials
Oral cancer (OC) is a devastating disease that takes the lives of lots of people globally every
year. The current spectrum of treatment modalities does not meet the needs of the patients …
year. The current spectrum of treatment modalities does not meet the needs of the patients …
The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions
A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …
cells. The mechanistic understanding of the pathways involved in tumor transformation has …
Nrf2 signaling pathway in chemoprotection and doxorubicin resistance: potential application in drug discovery
Doxorubicin (DOX) is extensively applied in cancer therapy due to its efficacy in suppressing
cancer progression and inducing apoptosis. After its discovery, this chemotherapeutic agent …
cancer progression and inducing apoptosis. After its discovery, this chemotherapeutic agent …
Novel extraction techniques and pharmaceutical activities of luteolin and its derivatives
Abstract Luteolin is a 3′, 4′, 5, 7 tetra hydroxyl flavonoid that exits in many plants, fruits,
and vegetable. Many methods of extraction, isolation, and purification are being used, and …
and vegetable. Many methods of extraction, isolation, and purification are being used, and …
Rationalizing the therapeutic potential of apigenin against cancer
Background Despite the remarkable advances made in the diagnosis and treatment of
cancer during the past couple of decades, it remains the second largest cause of mortality in …
cancer during the past couple of decades, it remains the second largest cause of mortality in …
Apoptosis and autophagy modulating dietary phytochemicals in cancer therapeutics: Current evidences and future perspectives
The global incidence of cancer and cancer‐related mortality is expected to rise in recent
years despite advancements in cancer diagnosis and therapeutics. Increasing evidences of …
years despite advancements in cancer diagnosis and therapeutics. Increasing evidences of …