A review on extrahepatic manifestations of chronic hepatitis C virus infection and the impact of direct-acting antiviral therapy

C Mazzaro, L Quartuccio, LE Adinolfi, D Roccatello… - Viruses, 2021 - mdpi.com
Extrahepatic manifestations are a feature of chronic hepatitis C virus (HCV) infection. In the
course of chronic HCV infection, about 70% of patients have one or more extrahepatic …

The cryoglobulinaemias

M Ramos-Casals, JH Stone, MC Cid, X Bosch - The Lancet, 2012 - thelancet.com
Cryoglobulins are immunoglobulins that precipitate in vitro at temperatures less than 37° C
and produce organ damage through two main pathways: vascular sludging (hyperviscosity …

Grazoprevir plus elbasvir in treatment-naive and treatment-experienced patients with hepatitis C virus genotype 1 infection and stage 4–5 chronic kidney disease (the …

D Roth, DR Nelson, A Bruchfeld, AM Liapakis, M Silva… - The Lancet, 2015 - thelancet.com
Background Chronic hepatitis C virus (HCV) infection in patients with stage 4–5 chronic
kidney disease increases the risk of death and renal graft failure, yet patients with hepatitis C …

[PDF][PDF] Diagnosis, management, and treatment of hepatitis C: an update

MG Ghany, DB Strader, DL Thomas, LB Seeff - Hepatology, 2009 - Wiley Online Library
Background The hepatitis C virus (HCV) is a major public health problem and a leading
cause of chronic liver disease. 5 An estimated 180 million people are infected worldwide. 6 …

Membranoproliferative glomerulonephritis—a new look at an old entity

S Sethi, FC Fervenza - New England Journal of Medicine, 2012 - Mass Medical Soc
This review discusses the causes, pathogenesis, and clinical management of
membranoproliferative glomerulonephritis, which accounts for 7 to 10% of biopsy-confirmed …

Cryoglobulinaemia

D Roccatello, D Saadoun, M Ramos-Casals… - Nature Reviews …, 2018 - nature.com
Cryoglobulinaemia refers to the serum presence of cryoglobulins, which are defined as
immunoglobulins that precipitate at temperatures< 37° C. Type I cryoglobulinaemia consists …

[HTML][HTML] Hepatitis C virus syndrome: A constellation of organ-and non-organ specific autoimmune disorders, B-cell non-Hodgkin's lymphoma, and cancer

C Ferri, M Sebastiani, D Giuggioli… - World journal of …, 2015 - ncbi.nlm.nih.gov
The clinical course of chronic hepatitis C virus (HCV) infection is characterized by possible
development of both liver and extrahepatic disorders. The tropism of HCV for the lymphoid …

Cryoglobulinemia—One Name for Two Diseases

P Cacoub, M Vieira, D Saadoun - New England Journal of …, 2024 - Mass Medical Soc
Key Points Cryoglobulinemia The causes of cryoglobulinemias are currently restricted to a
few hematologic disorders, systemic autoimmune diseases, and chronic infections. The …

Membranoproliferative glomerulonephritis: pathogenetic heterogeneity and proposal for a new classification

S Sethi, FC Fervenza - Seminars in nephrology, 2011 - Elsevier
Membranoproliferative glomerulonephritis (MPGN) is a pattern of injury that results from
subendothelial and mesangial deposition of Igs caused by persistent antigenemia and/or …

International diagnostic guidelines for patients with HCV-related extrahepatic manifestations. A multidisciplinary expert statement

C Ferri, M Ramos-Casals, AL Zignego, L Arcaini… - Autoimmunity …, 2016 - Elsevier
Hepatitis C virus (HCV) infection is responsible for both hepatic and extra-hepatic disorders
(HCV-EHDs); these latter are correlated on one hand clearly with HCV lymphotropism …