Applications of focused ultrasound in the brain: from thermoablation to drug delivery
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …
clinic represents the culmination of decades of research. Lying at the convergence of …
Non-invasive transcranial ultrasound stimulation for neuromodulation
Transcranial ultrasound stimulation (TUS) holds great potential as a tool to alter neural
circuits non-invasively in both animals and humans. In contrast to established non-invasive …
circuits non-invasively in both animals and humans. In contrast to established non-invasive …
Ultrasound technologies for imaging and modulating neural activity
Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …
humans is a major goal of neuroscience technology development. Established electrical and …
Intrinsic functional neuron-type selectivity of transcranial focused ultrasound neuromodulation
Transcranial focused ultrasound (tFUS) is a promising neuromodulation technique, but its
mechanisms remain unclear. We hypothesize that if tFUS parameters exhibit distinct …
mechanisms remain unclear. We hypothesize that if tFUS parameters exhibit distinct …
A tool for monitoring cell type–specific focused ultrasound neuromodulation and control of chronic epilepsy
Focused ultrasound (FUS) is a powerful tool for noninvasive modulation of deep brain
activity with promising therapeutic potential for refractory epilepsy; however, tools for …
activity with promising therapeutic potential for refractory epilepsy; however, tools for …
Sonication of the anterior thalamus with MRI-Guided transcranial focused ultrasound (tFUS) alters pain thresholds in healthy adults: A double-blind, sham-controlled …
Background: Transcranial focused ultrasound (tFUS) is a noninvasive brain stimulation
method that may modulate deep brain structures. This study investigates whether sonication …
method that may modulate deep brain structures. This study investigates whether sonication …
Systematic examination of low-intensity ultrasound parameters on human motor cortex excitability and behavior
Low-intensity transcranial ultrasound (TUS) can non-invasively modulate human neural
activity. We investigated how different fundamental sonication parameters influence the …
activity. We investigated how different fundamental sonication parameters influence the …
Current state of potential mechanisms supporting low intensity focused ultrasound for neuromodulation
J Dell'Italia, JL Sanguinetti, MM Monti… - Frontiers in human …, 2022 - frontiersin.org
Low intensity focused ultrasound (LIFU) has been gaining traction as a non-invasive
neuromodulation technology due to its superior spatial specificity relative to transcranial …
neuromodulation technology due to its superior spatial specificity relative to transcranial …
Transcranial focused ultrasound neuromodulation: a review of the excitatory and inhibitory effects on brain activity in human and animals
T Zhang, N Pan, Y Wang, C Liu, S Hu - Frontiers in Human …, 2021 - frontiersin.org
Non-invasive neuromodulation technology is important for the treatment of brain diseases.
The effects of focused ultrasound on neuronal activity have been investigated since the …
The effects of focused ultrasound on neuronal activity have been investigated since the …
[HTML][HTML] Sonothermogenetics for noninvasive and cell-type specific deep brain neuromodulation
Background Critical advances in the investigation of brain functions and treatment of brain
disorders are hindered by our inability to selectively target neurons in a noninvasive manner …
disorders are hindered by our inability to selectively target neurons in a noninvasive manner …