Characterizing metabolism in cancer is crucial for understanding tumor biology and for
developing potential therapies. Although most metabolic investigations analyze averaged …

Recent expansion in research in the field of lipidomics has been driven by the development
of new mass spectrometric tools and protocols for the identification and quantification of …

Fundamental advances in secondary ion mass spectrometry (SIMS) now allow for the
examination and characterization of lipids directly from biological materials. The successful …

Cholesterol plays an important role in determining the biophysical properties of biological
membranes, and its concentration is tightly controlled by homeostatic processes. The …

We discuss and illustrate recent advances that have been made to image the distribution of
metabolites among cells and tissues of plants using different mass spectrometry …

Mass spectrometry imaging (MSI) has proven to be extremely useful for applications such as
the spatial analysis of peptides and proteins in biological tissue, the performance …

The paper presents a general overview of the use of nanoparticles to perform sample
preparation. In this way the main uses of nanoparticles to carry out solid phase extraction …

Abstract Whole-body autoradiography ((WBA) or quantitative WBA (QWBA)),
microautoradiography (MARG), matrix-assisted laser desorption/ionization mass …

Mass spectrometry imaging and profiling of individual cells and subcellular structures
provide unique analytical capabilities for biological and biomedical research, including …

Application of mass spectrometry imaging (MS imaging) analysis to single cells was so far
restricted either by spatial resolution in the case of matrix-assisted laser …