L Zuo, ER Prather, M Stetskiv, DE Garrison… - International journal of …, 2019 - mdpi.com
It has been proposed that a chronic state of inflammation correlated with aging known as inflammaging, is implicated in multiple disease states commonly observed in the elderly …
HY Chung, DH Kim, EK Lee, KW Chung… - Aging and …, 2019 - ncbi.nlm.nih.gov
Age-associated chronic inflammation is characterized by unresolved and uncontrolled inflammation with multivariable low-grade, chronic and systemic responses that exacerbate …
Sarcopenia, an age-related decline in skeletal muscle mass and function, dramatically affects the quality of life. Although there is a consensus that sarcopenia is a multifactorial …
NJ Hunt, SWS Kang, GP Lockwood… - Computational and …, 2019 - Elsevier
While the liver demonstrates remarkable resilience during aging, there is growing evidence that it undergoes all the cellular hallmarks of aging, which increases the risk of liver and …
S Singh, TG Singh - Current Neuropharmacology, 2020 - ingentaconnect.com
A transcriptional regulatory nuclear factor kappa B (NF-ΚB) protein is a modulator of cellular biological activity via binding to a promoter region in the nucleus and transcribing various …
MC Marazita, A Dugour, MD Marquioni-Ramella… - Redox biology, 2016 - Elsevier
Oxidative stress has a critical role in the pathogenesis of Age-related Macular Degeneration (AMD), a multifactorial disease that includes age, gene variants of complement regulatory …
Y Huang, C Hu, H Ye, R Luo, X Fu, X Li… - Journal of …, 2019 - Wiley Online Library
The normal function of ovaries, along with the secretion of sex hormones, is among the most important endocrine factors that maintain the female sexual characteristics and promote …
RNA localization is highly regulated, with subcellular organization driving context- dependent cell physiology. Although proximity-based labelling technologies that use highly …
T Filardi, G Catanzaro, S Mardente, A Zicari… - International Journal of …, 2020 - mdpi.com
Gestational Diabetes Mellitus (GDM) is defined as glucose intolerance that develops in the second or third trimester of pregnancy. GDM can lead to short-term and long-term …