Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Collective cancer invasion with leader–follower organization is increasingly recognized as a
predominant mechanism in the metastatic cascade. Leader cells support cancer invasion by …

Transitions between epithelial and mesenchymal phenotypes–the epithelial to
mesenchymal transition (EMT) and its reverse the mesenchymal to epithelial transition …

Abstract Epithelial-to-Mesenchymal Transition (EMT) and its reverse–Mesenchymal to
Epithelial Transition (MET)–are hallmarks of cellular plasticity during embryonic …

Collective movement of epithelial cells drives essential multicellular organization during
various fundamental physiological processes encompassing embryonic morphogenesis …

Metabolic reprogramming is a hallmark of cancer metastasis in which cancer cells
manipulate their metabolic profile to meet the dynamic energetic requirements of the tumor …

Genetic and phenotypic heterogeneity contribute to the generation of diverse tumor cell
populations, thus enhancing cancer aggressiveness and therapy resistance. Compared to …

Cells migrate through 3D environments using a surprisingly wide variety of molecular
mechanisms. These distinct modes of migration often rely on the same intracellular …

One of the most important roles of cells is performing their cellular tasks properly for survival.
Cells usually achieve robust functionality, for example, cell-fate decision-making and signal …

Epithelial cells undergoing epithelial-to-mesenchymal transitions have often been shown to
behave as cancer stem cells, but the precise molecular connection remains elusive. At the …