Specialized pro-resolving mediator network: an update on production and actions
Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …
Resolution of inflammation: An organizing principle in biology and medicine
D Panigrahy, MM Gilligan, CN Serhan… - Pharmacology & …, 2021 - Elsevier
The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …
Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators
CN Serhan, BD Levy - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …
Pro-resolving lipid mediators: regulators of inflammation, metabolism and kidney function
Obesity, diabetes mellitus, hypertension and cardiovascular disease are risk factors for
chronic kidney disease (CKD) and kidney failure. Chronic, low-grade inflammation is …
chronic kidney disease (CKD) and kidney failure. Chronic, low-grade inflammation is …
Marine omega‐3 (n‐3) phospholipids: A comprehensive review of their properties, sources, bioavailability, and relation to brain health
For several decades, there has been considerable interest in marine‐derived long chain n‐3
fatty acids (n‐3 LCPUFAs) due to their outstanding health benefits. n‐3 LCPUFAs can be …
fatty acids (n‐3 LCPUFAs) due to their outstanding health benefits. n‐3 LCPUFAs can be …
The n-3 docosapentaenoic acid (DPA): A new player in the n-3 long chain polyunsaturated fatty acid family
G Drouin, V Rioux, P Legrand - Biochimie, 2019 - Elsevier
The n-3 docosapentaenoic acid (n-3 DPA) is less studied n-3 long-chain polyunsaturated
fatty acid (LCPUFA), compared to its counterparts eicosapentaenoic acid (EPA) and …
fatty acid (LCPUFA), compared to its counterparts eicosapentaenoic acid (EPA) and …
Protectins: Their biosynthesis, metabolism and structure-functions
Several lipoxygenase enzymes and cyclooxygenase-2 stereoselectively convert the
polyunsaturated fatty acids arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid …
polyunsaturated fatty acids arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid …
The protectin family of specialized pro-resolving mediators: potent immunoresolvents enabling innovative approaches to target obesity and diabetes
A western type diet and lifestyle play an important role in the development of chronic
diseases, yet little insight into the precise cellular and biomolecular mechanisms has …
diseases, yet little insight into the precise cellular and biomolecular mechanisms has …
Specialized Pro-Resolving Lipid Mediators: Endogenous Roles and Pharmacological Activities in Infections
FS Rasquel-Oliveira, MDV Silva, G Martelossi-Cebinelli… - Molecules, 2023 - mdpi.com
During an infection, inflammation mobilizes immune cells to eliminate the pathogen and
protect the host. However, inflammation can be detrimental when exacerbated and/or …
protect the host. However, inflammation can be detrimental when exacerbated and/or …
[HTML][HTML] Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential
Under physiological conditions the initiation, duration and amplitude of inflammatory
responses are tightly regulated to ensure the restoration of homeostasis. The resolution of …
responses are tightly regulated to ensure the restoration of homeostasis. The resolution of …