Epithelial cells are the most common cell type in all animals, forming the sheets and tubes
that compose most organs and tissues. Apical–basal polarity is essential for epithelial cell …

In eukaryotic cells, various membrane-bound organelles compartmentalize diverse cellular
activities in a spatially and temporally controlled manner. Numerous membraneless …

Cell signaling is a complex process. The faithful transduction of information into specific
cellular actions depends on the synergistic effects of many regulatory molecules, nurtured by …

Phase separation (PS) proteins form droplets to regulate myriad membraneless organelles
(MLOs) and cellular pathways such as transcription, signaling transduction and protein …

Lipid homeostasis is essential for normal cellular functions and dysregulation of lipid
metabolism is highly correlated with human diseases including neurodegenerative …

Formation of biomolecular condensates that are not enclosed by membranes via liquid-
liquid phase separation (LLPS) is a general strategy that cells adopt to organize …

Polarized cells rely on a polarized cytoskeleton to function. Yet, how cortical polarity cues
induce cytoskeleton polarization remains elusive. Here, we capitalized on recently …

Intracellular spaces are partitioned into separate compartments to ensure that numerous
biochemical reactions and cellular functions take place in a spatiotemporally controlled …

Liquid-liquid phase separation (LLPS) plays important roles in forming cellular
membraneless organelles. However, how host factors regulate LLPS of viral proteins during …

Despite recent studies implicating liquid-like biomolecular condensates in diverse cellular
processes, many biomolecular condensates exist in a solid-like state, and their function and …