(L)-malate salt of N-(4-{[6, 7-bis (methyloxy) quinolin-4-yl] oxy} phenyl)-N'-(4-fluorophenyl) cyclopropane-1, 1-dicarboxamide
AS clair Brown, P Lamb, WP Gallagher - US Patent 8,877,776, 2014 - Google Patents
Disclosed are malate salts of N-(4-{[6, 7-bis (methyloxy) quinolin-4-yl] oxy} phenyl)-N'-(4-?
uorophenyl) cyclopro pane-1, 1-dicarboxamide, including a (L)-malate salt, a (D) malate salt …
uorophenyl) cyclopro pane-1, 1-dicarboxamide, including a (L)-malate salt, a (D) malate salt …
Crystalline solid forms of N-{4-[(6, 7-dimethoxyquinolin-4-yl) oxy] phenyl}-N′-(4-fluorophenyl) cyclopropane-1, 1-dicarboxamide, processes for making, and methods …
DT Aftab, N Guz, S Lau, N Hamill, T Walker… - US Patent …, 2019 - Google Patents
The invention relates to novel crystalline solid forms of the chemical compound N-{4-[(6, 7-
dimethoxyquinolin-4-yl) oxy] phenyl}-N′-(4-fluorophenyl) cyclopropane-1, 1-dicarboxamide …
dimethoxyquinolin-4-yl) oxy] phenyl}-N′-(4-fluorophenyl) cyclopropane-1, 1-dicarboxamide …
c-Met modulators and methods of use
LC Bannen, DSM Chan, J Chen, LE Dalrymple… - US Patent …, 2015 - Google Patents
2007-03-14 Assigned to EXELIXIS, INC. reassignment EXELIXIS, INC. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: WANG, YONG …
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: WANG, YONG …
N-acyl ureas exhibiting anti-cancer and anti-proliferative activities
DL Flynn, PA Petillo, MD Kaufman - US Patent 8,278,331, 2012 - Google Patents
Compounds of the present invention? nd utility in the treat ment of mammalian cancers and
especially human cancers including, but not limited to, malignant melanomas, solid tumors …
especially human cancers including, but not limited to, malignant melanomas, solid tumors …
C-met modulator pharmaceutical compositions
JA Wilson, K Shah - US Patent 9,724,342, 2017 - Google Patents
7,579,473 B2 8, 2009 Bannen et al. 7.977, 345 B2 7/2011 Bannen et al. 8,067,436 B2
11/2011 Bannen et al. 8, 178,532 B2 5/2012 Bannen et al. 8,476,298 B2 7, 2013 Bannen et …
11/2011 Bannen et al. 8, 178,532 B2 5/2012 Bannen et al. 8,476,298 B2 7, 2013 Bannen et …
C-met modulator pharmaceutical compositions
JA Wilson, K Shah - US Patent 10,034,873, 2018 - Google Patents
2009/0274693 Al 11/2009 Gilmer et al. 2011/0059081 A1 3/2011 Bacus 2011/0077233 A1
3/2011 Bannen et al. 2012/0070368 Al 3/2012 Bannen et al. 2012/0184523 Al 7/2012 …
3/2011 Bannen et al. 2012/0070368 Al 3/2012 Bannen et al. 2012/0184523 Al 7/2012 …
C-Met modulator pharmaceutical compositions
JA Wilson, K Shah - US Patent 10,039,757, 2018 - Google Patents
2009/0274693 AL 11/2009 Gilmer et al. 2011/0059081 A1 3/2011 Bacus 2011/0077233 Al
3/2011 Bannen et al. 2012/0070368 A1 3/2012 Bannen et al. 2012/0184523 Al 7/2012 …
3/2011 Bannen et al. 2012/0070368 A1 3/2012 Bannen et al. 2012/0184523 Al 7/2012 …
Processes for preparing quinoline compounds and pharmaceutical compositions containing such compounds
JA Wilson, K Shah - US Patent 9,717,720, 2017 - Google Patents
2014/0057943 A1 2/2014 2014/0066444 A1 3, 2014 2014/O155396 A1 6, 2014
2014/017973.6 A1 6, 2014 2014/0200242 A1 7, 2014 2014/02284.01 A1 8, 2014 …
2014/017973.6 A1 6, 2014 2014/0200242 A1 7, 2014 2014/02284.01 A1 8, 2014 …
C-Met Modulators and Method of Use
LC Bannen, DSM Chan, J Chen… - US Patent App. 12 …, 2011 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
34397024&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
34397024&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Aminoquinazoline derivatives and their salts and methods of use
J Zhang, Y Zhang, W Zhang, B Liu, J Zhang… - US Patent …, 2015 - Google Patents
The present invention relates to the field of medicine. Pro vided herein are
aminoquinazoline derivatives, their salts and pharmaceutical formulations useful in …
aminoquinazoline derivatives, their salts and pharmaceutical formulations useful in …