Developing natural products as potential anti-biofilm agents

L Lu, W Hu, Z Tian, D Yuan, G Yi, Y Zhou, Q Cheng… - Chinese medicine, 2019 - Springer
Biofilm is a natural form of bacterial growth ubiquitously in environmental niches. The biofilm
formation results in increased resistance to negative environmental influences including …

Quorum sensing inhibitors as antipathogens: biotechnological applications

VC Kalia, SKS Patel, YC Kang, JK Lee - Biotechnology advances, 2019 - Elsevier
The mechanisms through which microbes communicate using signal molecules has inspired
a great deal of research. Microbes use this exchange of information, known as quorum …

[HTML][HTML] Recent advances in nanotechnology for eradicating bacterial biofilm

C Sahli, SE Moya, JS Lomas, C Gravier-Pelletier… - Theranostics, 2022 - ncbi.nlm.nih.gov
Microorganisms grouped together into spatially-organized communities called biofilms, are
the cause of dramatic chronic infections in plants, animals and humans. In this review, the …

Quorum sensing inhibitors: an overview

VC Kalia - Biotechnology advances, 2013 - Elsevier
Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the
emergence of multiple drug resistant strains. Most infectious diseases are caused by …

Exploiting quorum sensing to confuse bacterial pathogens

B LaSarre, MJ Federle - Microbiology and molecular biology …, 2013 - Am Soc Microbiol
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

Anti-quorum sensing natural compounds

HZ Asfour - Journal of microscopy and ultrastructure, 2018 - journals.lww.com
Increasing extent of pathogenic resistance to drugs has encouraged the seeking for new anti-
virulence drugs. Many pharmacological and pharmacognostical researches are performed …

Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

O Ciofu, T Tolker-Nielsen, PØ Jensen, H Wang… - Advanced drug delivery …, 2015 - Elsevier
Lung infection is the main cause of morbidity and mortality in patients with cystic fibrosis and
is mainly dominated by Pseudomonas aeruginosa. The biofilm mode of growth makes …

Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways

WRJD Galloway, JT Hodgkinson, SD Bowden… - Chemical …, 2011 - ACS Publications
Numerous species of bacteria employ a mechanism of intercellular communication known
as quorum sensing. This signaling process allows the cells comprising a bacterial colony to …

Agents that inhibit bacterial biofilm formation

N Rabin, Y Zheng, C Opoku-Temeng, Y Du… - Future medicinal …, 2015 - Taylor & Francis
In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …

Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing

TH Jakobsen, M van Gennip, RK Phipps… - Antimicrobial agents …, 2012 - Am Soc Microbiol
In relation to emerging multiresistant bacteria, development of antimicrobials and new
treatment strategies of infections should be expected to become a high-priority research …