[HTML][HTML] The role of lipid metabolic reprogramming in tumor microenvironment

K Yang, X Wang, C Song, Z He, R Wang, Y Xu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Metabolic reprogramming is one of the most important hallmarks of malignant tumors.
Specifically, lipid metabolic reprogramming has marked impacts on cancer progression and …

Recent advances in targeted nanomedicine as promising antitumor therapeutics

S Hejmady, R Pradhan, A Alexander, M Agrawal… - Drug discovery today, 2020 - Elsevier
Highlights•Nanocarriers with the ability to target tumors are being increasingly explored.•
Nanomedicine aid in maintaining a balance between efficacy and toxicity.•Recent advances …

Microfluidic tumor-on-a-chip model to evaluate the role of tumor environmental stress on NK cell exhaustion

JM Ayuso, S Rehman, M Virumbrales-Munoz… - Science …, 2021 - science.org
Solid tumors generate a suppressive environment that imposes an overwhelming burden on
the immune system. Nutrient depletion, waste product accumulation, hypoxia, and pH …

Robust nanovaccine based on polydopamine‐coated mesoporous silica nanoparticles for effective photothermal‐immunotherapy against melanoma

C Huang, L Zhang, Q Guo, Y Zuo… - Advanced Functional …, 2021 - Wiley Online Library
Nanoparticle‐based combination therapy strategy of photothermal therapy (PTT) and
immunotherapy is an attractive cancer treatment for ablating tumors and eliciting host …

Engineering polymeric prodrug nanoplatform for vaccination immunotherapy of cancer

L Zhou, B Hou, D Wang, F Sun, R Song, Q Shao… - Nano Letters, 2020 - ACS Publications
Neoantigen-based cancer vaccines are promising for boosting cytotoxic T lymphocyte (CTL)
responses. However, the therapeutic effect of cancer vaccines is severely blunted by …

[HTML][HTML] Tumor immune microenvironment and immunotherapy in non-small cell lung cancer: update and new challenges

S Xing, K Hu, Y Wang - Aging and disease, 2022 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is a serious threat to the health of older adults. Despite
the significant progress in immunotherapy, effective treatments for NSCLC remain limited …

[HTML][HTML] Tumor-infiltrating lymphocytes and CD8+ T cells predict survival of triple-negative breast cancer

H Vihervuori, TA Autere, H Repo, S Kurki… - Journal of cancer …, 2019 - Springer
Purpose Tumor inflammatory response was evaluated as a prognostic feature in triple-
negative breast cancer (TNBC) and compared with the clinical prognosticators of breast …

[HTML][HTML] Cancer metastasis chemoprevention prevents circulating tumour cells from germination

X Xie, Y Li, S Lian, Y Lu, L Jia - Signal transduction and targeted …, 2022 - nature.com
The war against cancer traces back to the signature event half-a-century ago when the US
National Cancer Act was signed into law. The cancer crusade costs trillions with …

[HTML][HTML] Immunocompetent cancer-on-chip models to assess immuno-oncology therapy

TI Maulana, E Kromidas, L Wallstabe… - Advanced Drug Delivery …, 2021 - Elsevier
The advances in cancer immunotherapy come with several obstacles, limiting its
widespread use and benefits so far only to a small subset of patients. One of the underlying …

[HTML][HTML] Bacterial outer membrane vesicles as a candidate tumor vaccine platform

S Wang, J Guo, Y Bai, C Sun, Y Wu, Z Liu… - Frontiers in …, 2022 - frontiersin.org
Cancer represents a serious concern for human life and health. Due to drug resistance and
the easy metastasis of tumors, there is urgent need to develop new cancer treatment …