A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium
Cryptosporidium spp are well recognised as causes of diarrhoeal disease during
waterborne epidemics and in immunocompromised hosts. Studies have also drawn …
waterborne epidemics and in immunocompromised hosts. Studies have also drawn …
Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis
INTRODUCTION Malaria remains a devastating global parasitic disease, with the majority of
malaria deaths caused by the highly virulent Plasmodium falciparum. The extreme AT-bias …
malaria deaths caused by the highly virulent Plasmodium falciparum. The extreme AT-bias …
Evolution of galactoglycerolipid biosynthetic pathways–from cyanobacteria to primary plastids and from primary to secondary plastids
Photosynthetic membranes have a unique lipid composition that has been remarkably well
conserved from cyanobacteria to chloroplasts. These membranes are characterized by a …
conserved from cyanobacteria to chloroplasts. These membranes are characterized by a …
PATRIC, the bacterial bioinformatics database and analysis resource
Abstract The Pathosystems Resource Integration Center (PATRIC) is the all-bacterial
Bioinformatics Resource Center (BRC)(http://www. patricbrc. org). A joint effort by two of the …
Bioinformatics Resource Center (BRC)(http://www. patricbrc. org). A joint effort by two of the …
Disbiome database: linking the microbiome to disease
Y Janssens, J Nielandt, A Bronselaer, N Debunne… - BMC microbiology, 2018 - Springer
Background Recent research has provided fascinating indications and evidence that the
host health is linked to its microbial inhabitants. Due to the development of high-throughput …
host health is linked to its microbial inhabitants. Due to the development of high-throughput …
EuPathDB: the eukaryotic pathogen genomics database resource
C Aurrecoechea, A Barreto, EY Basenko… - Nucleic acids …, 2017 - academic.oup.com
Abstract The Eukaryotic Pathogen Genomics Database Resource (EuPathDB,
http://eupathdb. org) is a collection of databases covering 170+ eukaryotic pathogens …
http://eupathdb. org) is a collection of databases covering 170+ eukaryotic pathogens …
Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites
The eukaryotic phylum Apicomplexa encompasses thousands of obligate intracellular
parasites of humans and animals with immense socio-economic and health impacts. We …
parasites of humans and animals with immense socio-economic and health impacts. We …
A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids
One of the first steps in understanding a protein's function is to determine its localization;
however, the methods for localizing proteins in some systems have not kept pace with the …
however, the methods for localizing proteins in some systems have not kept pace with the …
Companion: a web server for annotation and analysis of parasite genomes
S Steinbiss, F Silva-Franco, B Brunk, B Foth… - Nucleic acids …, 2016 - academic.oup.com
Currently available sequencing technologies enable quick and economical sequencing of
many new eukaryotic parasite (apicomplexan or kinetoplastid) species or strains. Compared …
many new eukaryotic parasite (apicomplexan or kinetoplastid) species or strains. Compared …
Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages
JJ Vasquez, CC Hon, JT Vanselow… - Nucleic acids …, 2014 - academic.oup.com
While gene expression is a fundamental and tightly controlled cellular process that is
regulated at multiple steps, the exact contribution of each step remains unknown in any …
regulated at multiple steps, the exact contribution of each step remains unknown in any …