The beneficial therapeutic effects of plant‐derived natural products for the treatment of sarcopenia

M Bagherniya, A Mahdavi… - Journal of Cachexia …, 2022 - Wiley Online Library
Sarcopenia is an age‐related muscle disorder typically associated with a poor quality of life.
Its definition has evolved over time, and several underlying causes of sarcopenia in the …

Experimental models of sarcopenia: bridging molecular mechanism and therapeutic strategy

S Mankhong, S Kim, S Moon, HB Kwak, DH Park… - Cells, 2020 - mdpi.com
Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength,
and functions in elderly people. It is accompanied by physical frailty, functional disability …

Mitochondria initiate and regulate sarcopenia

SE Alway, JS Mohamed, MJ Myers - Exercise and sport sciences …, 2017 - journals.lww.com
Sarcopenia is associated with increased levels of apoptosis (47) and reduced capabilities
for muscle regeneration (41) leading to muscle wasting. For this reason, many studies …

Resveratrol enhances exercise-induced cellular and functional adaptations of skeletal muscle in older men and women

SE Alway, JL McCrory, K Kearcher… - … Series A: Biomedical …, 2017 - academic.oup.com
Abstract Older men (n= 12) and women (n= 18) 65–80 years of age completed 12 weeks of
exercise and took either a placebo or resveratrol (RSV)(500 mg/d) to test the hypothesis that …

Age-related dysfunction in proteostasis and cellular quality control in the development of sarcopenia

HG Paez, CR Pitzer, SE Alway - Cells, 2023 - mdpi.com
Sarcopenia is a debilitating skeletal muscle disease that accelerates in the last decades of
life and is characterized by marked deficits in muscle strength, mass, quality, and metabolic …

Mechanisms underlying the effects of the green tea polyphenol EGCG in sarcopenia prevention and management

T Wang, H Xu, S Wu, Y Guo, G Zhao… - Journal of Agricultural …, 2023 - ACS Publications
Sarcopenia is prevalent among the older population and severely affects human health. Tea
catechins may benefit for skeletal muscle performance and protect against secondary …

[HTML][HTML] Lactobacillus paracasei PS23 decelerated age-related muscle loss by ensuring mitochondrial function in SAMP8 mice

LH Chen, SY Huang, KC Huang, CC Hsu… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Sarcopenia is a common impairment in the elderly population responsible for poor
outcomes later in life; it can be caused by age-related alternations. Only a few strategies …

The role of SIRT1 in skeletal muscle function and repair of older mice

MJ Myers, DL Shepherd, AJ Durr… - Journal of cachexia …, 2019 - Wiley Online Library
Abstract Background Sirtuin 1 (SIRT1) is a NAD+ sensitive deacetylase that has been linked
to longevity and has been suggested to confer beneficial effects that counter aging …

Impacts of green tea on joint and skeletal muscle health: Prospects of translational nutrition

HY Luk, C Appell, MC Chyu, CH Chen, CY Wang… - Antioxidants, 2020 - mdpi.com
Osteoarthritis and sarcopenia are two major joint and skeletal muscle diseases prevalent
during aging. Osteoarthritis is a multifactorial progressive degenerative and inflammatory …

Recent advances in nutraceuticals for the treatment of sarcopenic obesity

YC Kim, SW Ki, H Kim, S Kang, H Kim, G Go - Nutrients, 2023 - mdpi.com
Sarcopenic obesity, low muscle mass, and high body fat are growing health concerns in the
aging population. This review highlights the need for standardized criteria and explores …