Ubiquitination is a post-translational modification that targets specific proteins on their lysine
residues. Depending on the type of ubiquitination, this modification ultimately regulates the …

LSM1 is part of the cytoplasmic protein complex Lsm1–7-Pat1 and is likely involved in pre-
mRNA degradation by aiding U4/U6 snRNP formation. More research is needed to uncover …

The discovery of early diagnosis and prognostic markers for breast cancer can significantly
improve survival and reduce mortality. LSM1 is known to be involved in the general process …

Despite significant progress in the field of human breast cancer research and treatment,
there is a consistent increase in the incidence rate of 0.5 percent annually, posing …

Early diagnosis and identification of prognostic markers for ovarian cancer can significantly
improve survival and reduce mortality. The role of the YME1L1 signaling axis in genetic …

Early diagnosis of ovarian cancer and the discovery of prognostic markers can significantly
improve survival and reduce mortality. OPA3 protein exists in a structure called …

Background AlkB homolog 1, histone H2A dioxygenase (ALKBH1), a crucial enzyme
involved in RNA demethylation in humans, plays a significant role in various cellular …

The mitochondrial calcium uniporter (MCU) is a transmembrane protein facilitating the entry
of calcium ions into mitochondria from the cell cytosol. Maintaining calcium balance is …

Abstract Membrane-associated Ring-CH 5 (MARCH5) is a mitochondrial E3 ubiquitin ligase
playing a key role in the regulation of mitochondrial dynamics. In mammals, MARCH5 …

In this study, we aimed to elucidate the role of mitochondrial calcium uptake 1/2 (MiCU1/2) in
breast cancer (BRCA) by employing a comprehensive multi-omics approach. Unlike …