Lipids have essential biological functions in the body (eg, providing energy storage, acting
as a signaling molecule, and being a structural component of membranes); however, an …

CD36 is highly expressed in diverse tumor types and its expression correlates with
advanced stages, poor prognosis, and reduced survival. In cancer cells, CD36: 1) increases …

Hepatocellular carcinoma (HCC) is a metabolic disease with high mortality caused by
abnormal deposition of lipid droplets (LDs). The number and distribution of LDs can …

Metabolic reprogramming of cancer cells within the tumor microenvironment typically occurs
in response to increased nutritional, translation and proliferative demands. Altered lipid …

As the first identified N6‐methyladenosine (m6A) demethylase, fat mass and obesity‐
associated (FTO) protein is associated with fatty acid synthase (FASN) and lipid …

The ability of cancer stem cells (CSCs) to self-renew, differentiate, and generate new tumors
is a significant contributor to drug resistance, relapse, and metastasis. Therefore, the …

As a key factor in tumorigenesis, progression, recurrence and metastasis, the biological
properties, metabolic adaptations and immune escape mechanisms of CSCs are the focus …

Resistance to sorafenib has been documented in hepatocellular carcinoma (HCC) patients.
We investigated:(i) the correlation between adenosine triphosphate citrate lyase (ACLY) …

Cancer stem cells (CSCs) are a rare cancer cell population, responsible for the facilitation,
progression, and resistance of tumors to therapeutic interventions. This subset of cancer …

Cancer stem cells (CSCs) have high tumorigenicity, high metastasis and high resistance to
treatment. They are the key factors for the growth, metastasis and drug resistance of …